Influence of Different Prostheses on Postoperative Clinical Function in Total Knee Arthroplasty

NCT06617819 · tracked via the Priya Life Science China tracker

Sponsor

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Phase

Not applicable

Started

2024-09-30

Last updated

2024-10-01

Condition(s) studied

Knee Arthropathy

Investigational drug(s) / intervention(s)

CR prosthesisPS prosthesis

CR prosthesis: For patients undergoing simultaneous bilateral knee arthroplasty, different prostheses (CR vs. PS) were randomized to the left or right knee.

PS prosthesis: For patients undergoing simultaneous bilateral knee arthroplasty, different prostheses (CR vs. PS) were randomized to the left or right knee.

Study summary

Exploring differences in knee function after surgery with different types of prostheses(Cruciate ligament retaining(CR) VS. posterior stabilizing(PS))

Eligibility

Sex

ALL

Min age

45 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: 1. Age 45-80 years, any gender, BMI \< 35 kg/m2 2. Initial diagnosis of bilateral knee OA (Kellgren-Lawrence classification grades 3 or 4). Patients who are to undergo simultaneous primary bilateral knee arthroplasty 3. Inversion deformity ≤ 15° 4. Posterior cruciate ligament integrity Exclusion Criteria: 1. History of knee surgery (ligament, osteotomy, etc.) 2. knee flexion\<90°. 3. flexion contracture of one knee \> 10° 4. Comorbidity with other diseases, such as peripheral neuropathy, malignant tumors, rheumatism, etc. 5. Posterior cruciate ligament injury 6. Those assessed to be intolerant of surgery

Primary outcome measure(s)

Knee Society Score, KSS — 6 weeks, 3 months, 6 months, 12 months, 24 months after surgery
Use of Knee Society Score scales for assessment. Including pain, mobility, stability, the patient\'s ability to walk, up and down the stairs, etc. on the assessment, 85-100 is excellent, 70-84 is good, 60-69 is pass, less than 60 is poor

Trial sites (1)

Facility	City	Region	Status
Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University	Nanjing	Jiangsu

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06617819 on ClinicalTrials.gov ↗ ← All trials in China