Intermittent hypoxia intervention: The intermittent hypoxia protocol refers to 6 cycles of 10 minutes hypoxia inhaling interval by 5 minutes normoxia, which is performed twice a day (at least 6 hours apart) in 7 days.
Study summary
This study aims to explore the safety and efficacy of intermittent hypoxia intervention on patients with colorectal cancer.
Eligibility
Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria:
* Patients with colorectal cancer between ages of 18 and 65 years.
* Colorectal cancer stage Ⅰ,Ⅱ.
* Subjects or their legally authorized representative can provide informed consent.
Exclusion Criteria:
* History of cardiovascular, cerebrovascular, dermatological, and hematological diseases.
* History of pulmonary, hepatic, kidney, dermatologic and hematologic diseases.
* History of pregnancy, hypertension, diabetes mellitus, obesity, sleep apnea and neurological disorders.
* History of substance abuse.
* Participating in other drug or medical device studies.
* History of organ transplantation, including allogeneic stem cell and immune cell transplantation.
* Recent severe infection within 4 weeks.
* Received cancer treatment, including chemotherapy and radiotherapy, within 4 weeks.
* Underwent major surgery within 28 days.
Primary outcome measure(s)
Incidence of adverse reactions — During the 7-day treatment Adverse reactions included headache, vomiting, diarrhea, fatigue, dizziness and insomnia.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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