This clinical trial study is conducted to detect the imaging characteristics of the patients with Parkinson's diseases (PD) by 7-Tesla (7T) magnetic resonance imaging (MRI).
Eligibility
Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* the patients with PD who was diagnosed by the experienced neurologist specializing in movement disorders
Exclusion Criteria:
* the patients with brain disorders such as cerebrovascular disease, brain tumors, epilepsy, other neurodegenerative disease;
* psychiatric disorders with impaired cognitive function;
* contraindications to MRI.
Primary outcome measure(s)
The change in motor symptoms in PD patients. — 5 year after the conduction of clinical trial The patient's clinical state was evaluated according to the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) and H-Y scale. The former scale total score ranges from 0 to 199, with higher scores indicating more severe symptoms in patients. H-Y scale categorizes PD into five stages with higher stages indicate more severe symptoms.
Comparison will be performed from examinations for case-control study versus for baseline and 5-year follow-up timepoints.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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