A Study of B013 in Combination With Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer.
Condition(s) studied
Investigational drug(s) / intervention(s)
B013: B013: The subjects will receive IV dose of B013 600 mg on Day 1 and 15 of the first 28-day cycle, then on Day 1 of each subsequent 28-day cycle.
Paclitaxel: Paclitaxel: 80 mg/m\^2 is administered weekly on Day 1, 8, 15 of each 28-day cycle.
Placebo: Placebo: The subjects will receive IV dose of placebo matched to B013 on Day 1 and 15 of the first 28-day cycle, then on Day 1 of each subsequent 28-day cycle.
Study summary
To evaluate the efficacy and safety of B013 in patients with platinum-resistant recurrent ovarian cancer.
Eligibility
Primary outcome measure(s)
- Progression-free survival (PFS) — Approximately 2 years
From the date of randomization to the date of progression disease or death , whichever occurred first.
Trial sites (17)
| Facility | City | Region | Status |
|---|---|---|---|
| Beijing Cancer Hospital | Beijing | China | Recruiting |
| The First Affiliated Hospital of Bengbu Medical University | Bengbu | China | Recruiting |
| XiangYa Hospital CentralSouth University | Changsha | China | Recruiting |
| Fujian Cancer Hospital | Fuzhou | China | Recruiting |
| Sun Yat-sen Memorial Hospital, Sun Yat-sen University | Guangzhou | China | Recruiting |
| Cancer Hospital of Shandong First Medical University | Jinan | China | Recruiting |
| Qilu Hospital of Shandong University | Jinan | China | Recruiting |
| Yunnan Cancer Hospital | Kunming | China | Recruiting |
| Guangxi Medical University Cancer Hospital | Nanning | China | Recruiting |
| Fudan University Shanghai Cancer center | Shanghai | China | Recruiting |
| The Obstetrics & Gynecology Hospital of Fudan University | Shanghai | China | Recruiting |
| The Second Hospital of Hebei Medical University | Shijiazhuang | China | Recruiting |
| Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Wuhan | China | Recruiting |
| Shananxi Provincial Cancer Hospital | Xi'an | China | Recruiting |
| The First Affiliated Hospital of Xiamen University | Xiamen | China | Recruiting |
| Yibin city second people's Hospital | Yibin | China | Recruiting |
| Henan Cancer Hospital | Zhengzhou | China | Recruiting |
More Shanghai Jiaolian Drug Research and Development Co., Ltd trials in China
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06434610 on ClinicalTrials.gov ↗ ← All trials in China