A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD

NCT06346600 · tracked via the Priya Life Science China tracker

Sponsor

Skyline Therapeutics

Phase

Observational

Started

2025-04-02

Last updated

2026-09-01

Condition(s) studied

Neovascular (Wet) Age-related Macular Degeneration

Investigational drug(s) / intervention(s)

SKG0106

SKG0106: Non-interventional (observational) study, long-term follow-up safety and efficacy assessments up to 5 years post SKG0106 injection.

Study summary

This is a Prospective, Non-interventional, Multicenter, Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients with Neovascular (Wet) Age-related Macular Degeneration (nAMD). All subject who completed the parent clinical study (NCT06213038 and NCT05986864) will undergo safety and efficacy assessments up to 5 years post study drug injection.

Eligibility

Sex

ALL

Min age

50 Years

Max age

—

Healthy volunteers

Inclusion Criteria: Subjects who only meet all of the following criteria are eligible for this study: * nAMD subjects who have been enrolled in the SKG0106-related study and received SKG0106 injection; * Subjects who voluntarily sign an informed consent form (ICF) and comply with the protocol to complete the study Exclusion Criteria: * Subjects who are judged by the investigator unsuitable for this study

Primary outcome measure(s)

Type, severity, and incidence of ocular and systemic adverse events (AEs), serious adverse events (SAEs), and adverse events of special interest (AESIs) — 5 years post study drug injection

Trial sites (10)

Facility	City	Region	Status
Ophthalmic Consultants of Boston	Boston	Massachusetts	Not Yet Recruiting
Retina Consultants of Texas	Katy	Texas	Not Yet Recruiting
Wagner Macula & Retina Center	Norfolk	Virginia	Not Yet Recruiting
The Second Hospital Of Anhui Medical University	Hefei	Anhui	Not Yet Recruiting
Zhejiang Provincial People's Hospital	Hangzhou	Zhejiang	Not Yet Recruiting
Eye Hospital, WMU (Zhejiang Eye Hospital)	Wenzhou	Zhejiang	Not Yet Recruiting
Beijing Hospital	Beijing	China	Not Yet Recruiting
Peking Union Medical College Hospital	Beijing	China	Recruiting
EYE & ENT Hospital of Fudan University	Shanghai	China	Recruiting
Xinhua Hospital Affiliated To Shanghai Jiao Tong University School Of Medicine	Shanghai	China	Not Yet Recruiting

Other trials for the same condition

AI vs. Physician for Anti-VEGF Decision-Making: An RCT Starting soon

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06346600 on ClinicalTrials.gov ↗ ← All trials in China