Clinical Trials in China / NCT06340945
Recruiting
Not applicable
The Outcomes of Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules
NCT06340945 · tracked via the Priya Life Science China tracker
Condition(s) studied
Thyroid Nodules
Investigational drug(s) / intervention(s)
ultrasound-guided thermal ablation
ultrasound-guided thermal ablation: microwave ablation, radio frequency ablation, laser ablation
Study summary
1. To evaluate the clinical outcomes of ultrasound-guided thermal ablationfor the treatment of benign thyroid nodules;
2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of benign thyroid nodules
Eligibility
Inclusion Criteria:
* \[1\]confirmation of benign nodule status on two separate fine- needle aspiration (FNA) or core-needle biopsy (CNB) \[2\]no suspicious malignant features on ultrasound examination \[3\]report of cosmetic and/ or symptomatic problems or concern of nodules growing rapidly or malignant transformation \[4\]refusal or ineligibility for surgery \[5\]follow-up time ≥6months
Exclusion Criteria:
1. follicular neoplasm or malignancy findings on biopsy
2. nodules with benign result on biopsy had suspicious of malignancy in US, including marked hypoechoic, ill-defined margins, taller-than-wide shape or microcalcifications
3. patients with cystic nodules
4. patients with contra-lateral vocal cord par- alysis
5. previous radiation to the head and neck
6. ; follow- up time less than 6 months
Primary outcome measure(s)
- volume reduction rate — through study completion, an average of 6 months
The volume reduction rate (VRR)was calculated by the equations: VRR=(\[initial volume-final volume\] × 100)/initial volume - rate of nodule regrowth — through study completion, an average of 1 months
Regrowth was defined as ≥50% volume increase compared to the previously recorded smallest volume during the follow-up
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Chinese PLA General Hospital | Beijing | China | Recruiting |
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Other trials for the same condition
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06340945 on ClinicalTrials.gov ↗ ← All trials in China