Health Problems in PregnancyPregnancy OutcomesGestational DiabetesGestational HypertensionPreterm BirthObesityMother-Infant InteractionChild DevelopmentAnemia
Investigational drug(s) / intervention(s)
No Interventions
No Interventions: No intervention This is an observational study without any intervention
Study summary
The PKUBC-WF is a prospective cohort study carried out in Weifang city of Shandong, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal and child health. Data are collected regarding environmental, nutritional and lifestyle exposures as well as short-term and long-term health outcomes of mothers and their children from birth to before 18 years old. Biological samples including peripheral blood, urine, placenta, umbilical cord, cord blood, and faeces are also collected.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Pregnant woman
1. Pregnant women, 6-13\^+6 gestational weeks
2. Resided in Weifang in the past half years and have no plan to move out after delivery
3. Pregnant women who plan to have antenatal care and delivery in Weifang maternal\&Child Hospital.
4. Pregnant women who is willing to participate in this study with informed consent
* Pregnant woman's husband
1. His wife was eligible for enrollment
2. He is the biological father of the child (his wife's current pregnancy)
3. Pregnant women's husband who is willing to participate in this study with informed consent
* Offspring 4. Children born to pregnant women who met the inclusion criteria after enrolling in this study.
5\. Before the age of 8 years, his/her mother provided written informed consent. 6. After 8 years old, he/she agreed to continue this study and signed the informed consent.
Exclusion Criteria:
* Participants who cannot communicate normally.
Primary outcome measure(s)
Numbers and morbidity of participants with pregnancy complications — At delivery Including gestational diabetes, gestational hypertension, anemia, and hypothyroidism during pregnancy
Numbers and morbidity of participants with adverse pregnancy outcomes — At delivery Including preterm birth, low birth weight, macrosomia, abortion, stillbirth, and birth defects.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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