1. The correlations of serum vitamin D level, serum calcium level and osteoporosis degree with disease severity, treatment response, incidence of Post-Herpes zoster(PHN) and disease prognosis in Herpes zoster(HZ) patients were studied.
2. To investigate the role of inflammation-related factors and immune-related factors in the occurrence and development of HZ mediated by low vitamin D level.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Age ≥18 years.
* The patient was diagnosed with herpetic neuralgia and the course of disease was ≤3 months.
* Can cooperate with the completion of inquiry and scale evaluation.
Exclusion Criteria:
* Severe spinal disease (fracture, malignancy, acute or chronic infection) confirmed by previous spinal surgery or imaging.
* Previous history of head trauma.
* Have autoimmune diseases (systemic lupus erythematosus, rheumatoid arthritis, leucothrombocytopenia).
* Suffering from mental disorders, intellectual disability, epilepsy and other diseases.
* A history of substance abuse, drug abuse or alcohol abuse.
* Pregnant or breastfeeding women.
* And recent participation in other clinical studies.
Primary outcome measure(s)
Serum 25-hydroxyvitamin D levels — herpetic neuralgia <3 month Vitamin D deficiency: \< 20 nmol/L. Vitamin D deficiency: 20-30 nmol/L. Normal vitamin D: \> 30 nmol/L.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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