Relationship of the cognitive leisure activity levels, cognitive function, and MRI characteristics.
Relationship of the cognitive leisure activity levels, cognitive function, and MRI characteristics.: The cognitive leisure activity levels, cognitive function, and MRI characteristics in people in the preclinical stage of Alzheimer's Disease (AD).
Study summary
The goal of this clinical trial is aims to:
1. Translate and culturally adapt the Cognitive Leisure Activity Scale (CLAS) into Chinese and Conduct reliability and validity tests for the Chinese version of CLAS.
2. Investigate the correlation between cognitive leisure activity levels and cognitive function in the preclinical stage of Alzheimer's Disease (AD).
3. Clarify the regulatory mechanisms of cognitive leisure activity levels on the neural circuits of patients in the preclinical stage of AD.
Eligibility
Sex
ALL
Min age
60 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Clinical diagnosis of Mild Cognitive Impairment (MCI) and Subjective Cognitive Decline (SCD)
* Age ≥ 60 years
* Capable of normal communication in Mandarin，possesses a certain level of comprehension and judgment.
Exclusion Criteria:
* Individuals with severe hearing or language impairments, or with severe physical illnesses that are unable to cooperate with the survey
* Individuals with pacemakers, metallic implants, cochlear implants, claustrophobia, and other contraindications for MRI examination.
Primary outcome measure(s)
Cognitive leisure activity levels — Baseline The Chinese version of Cognitive \& leisure activity scale will be used. Utilizing the Likert 5-point scale with 16 items, total score ranges from 0 to 80 points，higher scores signify increased cognitive leisure activity levels. An abnormal level is determined if the score is below 25 points.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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