🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Clinical Trials in China / NCT06188624
Recruiting Phase 1

Clinical Trial of TQB2922 for Injection in Patients With Advanced Cancers

NCT06188624 · tracked via the Priya Life Science China tracker
Sponsor
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
Phase
Phase 1
Started
2024-02-01
Last updated
2025-04-25

Condition(s) studied

Advanced Cancer

Investigational drug(s) / intervention(s)

TQB2922 for injection →

TQB2922 for injection: TQB2922 for injection is administrated to patients with advanced cancers, 28 days as a treatment cycle

Study summary

This is a Phase I study to evaluate the safety, tolerability, and efficacy of TQB2922 for injection in subjects with advanced cancers

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: * Subjects voluntarily join this study, sign the informed consent form, and have good compliance; * Age: 18-75 years; Eastern Cooperative Oncology Group (ECOG) score: 0-1 ; Expected survival of more than 3 months; * Histologically or cytologically diagnosed with advanced cancers; * Subjects with advanced malignancies who have failed standard therapy or lack effective treatment; * Major organs are functioning well; * Female and male subjects of childbearing potential should agree to practice contraception during the study and until 6 months after the completion of the study. Exclusion Criteria: * Current concomitant or ever presented with other malignancies within 2 years prior to the first dose; * Unresolved toxicity of Grade 1 or above according to CTCAE due to any prior anti-tumor therapy; * Significant surgical treatment, biopsy, or significant traumatic injury within 28 days prior to the first dose; * Long-term unhealed wounds or fractures * Cerebrovascular accident (including transient ischemic attack, intracerebral hemorrhage, cerebral infarction), deep vein thrombosis, and pulmonary embolism within 6 months prior to the first dose; * A history of psychotropic drug abuse and cannot be abstained, or have a mental disorder; * Subjects with any severe and/or uncontrolled disease; * History of live attenuated vaccination within 2 weeks prior to the first dose or planned live attenuated vaccination during the study; * Previous history of unexplained severe allergies, hypersensitivity to monoclonal antibodies or exogenous human immunoglobulins, or hypersensitivity to TQB2922 for injection or its excipients; * According to the judgment of the investigator, there are concomitant diseases that seriously endanger the safety of the patients or affect the completion of the study, or subjects who are considered to be unsuitable for enrollment for other reasons.

Primary outcome measure(s)

Trial sites (17)

FacilityCityRegionStatus
Chongqing University Cancer Hospital Chongqing Chongqing Municipality Not Yet Recruiting
Sun Yat-sen University Cancer Center Guangzhou Guangdong Recruiting
The first affiliated hospital of Guangzhou medical university Guangzhou Guangdong Not Yet Recruiting
Harbin Medical University Cancer Hospital Harbin Heilongjiang Not Yet Recruiting
Henan Cancer Hospital Zhengzhou Henan Not Yet Recruiting
Henan Provincine People's Hospital Zhengzhou Henan Not Yet Recruiting
The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Not Yet Recruiting
The Second Xiangya Hospital of Central South University Changsha Hunan Not Yet Recruiting
Hunan Cancer Hospital Changsha Hunan Not Yet Recruiting
Nanjing Drum Tower Hospital Nanjing Jiangsu Not Yet Recruiting
Affiliated Zhongshan Hospital of Dalian University Dalian Liaoming Not Yet Recruiting
Department of Medical Oncology, The First Hospital of China Medical University Shenyang Liaoning Not Yet Recruiting
The First Affiliated Hospital of Xi'an Jiaotong University Xi'an Shaanxi Not Yet Recruiting
Shanghai Pulmonary Hospital Shanghai Shanghai Municipality Not Yet Recruiting
Affiliated Hospital of North Sichuan Medical College Nanchong Sichuan Not Yet Recruiting
Tianjin Medical University Cancer Institute and Hospital Tianjin Tianjin Municipality Not Yet Recruiting
Yunnan Cancer Hospital Kunming Yunnan Not Yet Recruiting

More Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. trials in China

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06188624 on ClinicalTrials.gov ↗ ← All trials in China