Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science

NCT06085690 · tracked via the Priya Life Science China tracker

Sponsor

Fudan University

Phase

Not applicable

Started

2023-09-04

Last updated

2025-11-17

Condition(s) studied

CRBSI - Catheter Related Bloodstream InfectionEvidence-based Nursing PracticeCentral Venous Catheter Related Bloodstream InfectionCentral Venous Catheter Associated Bloodstream InfectionCentral Line InfectionCLABSI - Central Line Associated Bloodstream InfectionQuality Improvement

Investigational drug(s) / intervention(s)

evidence-based intervention Plan for the Prevention of CRBSI in ICU patients

evidence-based intervention Plan for the Prevention of CRBSI in ICU patients: On the basis of routine nursing, the "evidence-based intervention Plan for the Prevention of CRBSI in ICU patients" was implemented for intervention.

Study summary

The goal of this type of study is to construct the continuous quality promotion project "ICU-NO CRBSI(Catheter-Related Bloodstream Infection , CRBSI)" based on improvement science, and to verify its effect in the prevention of central venous catheter-related bloodstream infection and continuous quality improvement in ICU ( Intensive Care Unit , ICU) through multi-center implementation and two rounds of improvement.

The main question\[s\] it aims to answer are:

What is the incidence of catheter-related bloodstream infection in the ICU of participating units? How compliant are health care providers in the ICU with evidence-based sensory control practices for the prevention of catheter-associated bloodstream infection?

Participants will be provided with the hospital's routine CVC (Central Venous Catheter ,CVC) care practices and CVC quality improvement measures based on evidence-based guidelines What technical and cultural support is needed to implement quality and safety improvement measures?

Eligibility

Sex

ALL

Min age

—

Max age

—

Healthy volunteers

Accepted

Inclusion Criteria: * ICU stay over 48 hours * CVC was placed for more than 24 hours Exclusion Criteria: * Pregnant patients * Patients with a history of CRBSI infection * Patients with central venous catheterization were brought in from other hospitals

Primary outcome measure(s)

Incidence of CRBSI — 1year
CRBSI incidence ratio — 1 year
Ratio of CRBSI incidence per quarter (IRR)

Trial sites (1)

Facility	City	Region	Status
ZhongShan Hospital Affilicated to Fudan University	Shanghai	Shanghai Municipality	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06085690 on ClinicalTrials.gov ↗ ← All trials in China