There was no intervention as this was an observational study.
There was no intervention as this was an observational study.: There was no intervention as this was an observational study.
Study summary
Alzheimer's disease (AD) presents a significant socio-economic challenge globally, with China experiencing a notable rise in its prevalence. This study addresses critical gaps in understanding AD's economic burden and quality of life (QoL) impacts on patients and caregivers in Mainland China.
Eligibility
Sex
ALL
Min age
40 Years
Max age
100 Years
Healthy volunteers
No
Diagnosed according to the National Institute on Aging-Alzheimer's 1.Association (NIA-AA) criteria for aMCI and AD.
2.Clinical Dementia Rating (CDR) score greater than or equal to 0.5 3.Have good visual, auditory, and language functions, or can complete neuropsychological assessments after correction.
4.Participants or their legal representatives sign informed consent. Exclusion criteria
1. History of stroke with neurological focal signs and imaging findings consistent with cerebral small vessel disease (Modified Fazekas score ≥2).
2. Presence of mental or neurological developmental delay.
3. Presence of other known conditions that may cause cognitive impairment.
4. Diagnosis of a disease that prevents completion of cognitive assessments.
5. Refusal to sign informed consent at baseline.
Primary outcome measure(s)
Direct medical expenses — baseline Direct medical expenses refer to the expenses incurred by patients and/or their families for medical and health services related to Alzheimer's disease
Direct non-medical expenses — baseline The direct non-medical costs of Alzheimer's disease include care costs, home facilities and repair costs, health care products costs and related expenses incurred during medical treatment. The cost of care includes the salary of caregivers, the expenses of external caregivers, and the travel expenses of caregivers
overhead expenses — baseline Indirect costs include the economic loss caused by patients' inability to work, the decrease in the income of informal caregivers, the treatment expenses of caregivers' psychological diseases and the medical expenses incurred by patients with Alzheimer's disease or caregivers due to accidental injuries.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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