MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Condition(s) studied

Investigational drug(s) / intervention(s)

Magnetic Resonance Elastography: Undergo MRE and routine MRI

Assessment and Recording: Undergo grading and recording of tumor stiffness and adhesion during surgery

Study summary

In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.

The stiffness of the tumor dictates the complexity of removal, while strong adhesion presents additional challenges during the surgical procedure.

This clinical trial aims to assess the clinical utility of magnetic resonance elastography (MRE), in evaluating the stiffness and adhesion of spinal cord tumors and guiding surgical planning to selecting the most appropriate surgical approach for patients with spinal cord tumors.

Eligibility

Primary outcome measure(s)

• Surgical assessment of tumor stiffness — Baseline to 6 weeks
  The surgeon will score the tumor stiffness in seven aspects, ranging from 1 to 5 points: Tumor size; Shape of tumor; Tumor texture; Stiffness of the tumor's capsule; Stiffness of the tumor's central region; Primary methods of tumor removal; Features of tumor's capsule.
• Surgical assessment of tumor adhesion — Baseline to 6 weeks
  The surgeon will score the tumor's adhesion based on seven aspects, ranging from 1 to 4 points: Stripping instruments; Frequency of use of sharp instruments; Adhesion range; Degree of tumor resection; Cranial nerve anatomy preservation; Brain tissue anatomy preservation; Neurological function (compared with preoperative).

Trial sites (1)

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