Randomized Controlled Clinical Study on the Reduction of Tumor Marker Levels in Breast Cancer Patients by Huaier Granules

Inclusion Criteria: * 18 ≤ age ≤ 75 years old, regardless of gender. * Postoperative pathological diagnosis of breast cancer. * Imaging or pathological examination without evidence of recurrence or metastasis. * If tumor markers are elevated, it is necessary to go to the corresponding department for medical treatment or issue a corresponding examination when necessary to exclude recurrence, metastasis or the second primary tumor of breast cancer. * One or more tumor markers in CEA/CA125/CA153 exceed the upper limit of normal values. * The liver and kidney functions meet the following conditions: AST and ALT\< 3 ULN, total bilirubin ≤ 2 ULN, and blood creatinine\<1.5 ULN; * Other laboratory tests meet the following requirements: Hb ≥ 9g/dl, platelet count ≥ 60 × 10\^9/L, absolute neutrophil count\>1.0 × 10\^9/L. * The patient's ECOG physical state score is 0 or 1. * The subjects participated in this study voluntarily and signed an informed consent form. Exclusion Criteria: * Diagnosed as any other malignant tumor within the 5 years prior to enrollment, except for malignant tumors with low risk of metastasis and death (5-year survival rate\>90%), such as fully treated basal cell or squamous cell skin cancer or cervical cancer in situ. * Imaging or pathological confirmation of recurrence and metastasis. * Serious infections (CTCAE\>Level 2) occurred within the first 4 weeks of enrollment, such as severe pneumonia, bacteremia, and infection complications that require hospitalization; Symptoms and signs of infection or the need for oral or intravenous antibiotic treatment within 2 weeks prior to enrollment, excluding the use of prophylactic antibiotics. * Suffering from severe acute and chronic diseases. * Suffering from severe diabetes whose blood sugar cannot be effectively controlled. * Patients who are unable to take oral medication, those who are allergic to the ingredients of Huaier granules, and pregnant or lactating women. * Drug abusers, or those who suffer from psychological or mental illnesses that may interfere with research compliance. * The researcher believes that it is not suitable to participate in this study.