Atherectomy Followed With a Drug Coated Balloon in the Treatment of Long Femoropopliteal Lesions

Inclusion Criteria: 1. Subject must be between 18 and 85 years old; 2. Chronic, symptomatic lower limb ischemia defined as Rutherford categories 3-5; 3. Stenotic, restenosis, or occlusive lesions in the native femoropopliteal artery which meets all of the following criteria: Stenotic lesion(\>70% diameter stenosis) \>15cm or Chronic total occlusion between 6-15cm; Target vessel is 3.0 to 7.0 mm in diameter (visual estimate); Guidewire must be across the target lesion within the true lumen before study randomization; 4. Patent distal popliteal artery and at least one patent distal runoff; 5. Willing to comply with the follow-up evaluation; 6. Written informed consent prior to any study procedures. Exclusion Criteria: 1. Women during pregnancy and lactation, or patients with baby planning; 2. Life expectancy\<2 years; 3. Target lesion/vessel with in-stent restenosis 4. Target restenosis/vessel lesion previously treated with drug coated balloon or atherectomy \<12 months 5. Subjects s who are currently participating in other interventional drug or device trials; 6. Angiographic evidence of thrombus within the target vessel 7. Subjects have a history of stroke within 3 months; 8. Subjects have a history of myocardial infarction, thrombolytic therapy, or angina pectoris within 2 weeks; 9. Concomitant Renal failure with a serum creatinine\>2.0mg/dl; Subjects with known allergy to heparin, low molecular weight heparin, and contrast agents.