Institute of Hematology & Blood Diseases Hospital, China
Phase
Observational
Started
2022-11-01
Last updated
2023-05-23
Condition(s) studied
Follicular Lymphoma
Study summary
This study is planned to prospectively observe and verify the efficacy and safety of induction therapy with obinutuzumab in combination with lenalidomide followed by maintenance therapy with obinutuzumab and lenalidomide in patients with R/R FL in a real-world setting in a Chinese population.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Patients must meet the following criteria for study entry::
* Signed Informed Consent Form
* Age ≥ 18 years at enrollment
* At least one prior line of systemic (Stage III-IV) follicular lymphoma therapy
* Relapsed or refractory to front-line anti-lymphoma therapy; refractory is defined as: tumor shrinkage of less than 50% or disease progression after 4 cycles of standard regimen chemotherapy; response to standard regimen chemotherapy, relapse within 24 months; 2 or more relapses, meeting one of the above criteria as refractory lymphoma.
* Conditional treatment with obinutuzumab in combination with lenalidomide
Exclusion Criteria:
* Patients currently participating or planning to participate in any interventional clinical trial
* Any other reason that, in the opinion of the investigator, makes the patient unsuitable for this study
Primary outcome measure(s)
overall response rate(ORR) — 24 weeks Proportion of patients with complete response (CR) and partial response (PR) after the end of induction therapy.
Trial sites (1)
Facility
City
Region
Status
Institute of Hematology and Blood Diseases Hospital ,Chinese Academy of Medical Sciences
Tianjin
China
Recruiting
More Institute of Hematology & Blood Diseases Hospital, China trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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