The First Affiliated Hospital with Nanjing Medical University
Phase
Not applicable
Started
2022-02-01
Last updated
2024-11-12
Condition(s) studied
Hepatic Ischemia
Investigational drug(s) / intervention(s)
sodium bicarbonate Ringer's solution
sodium bicarbonate Ringer's solution: Sodium bicarbonate Ringer's solution was used in Group A as intraoperative intravenous fluids. Lactate Ringer's solution was used in Group B as intraoperative intravenous fluids.
Study summary
Compared the effects of Sodium bicarbonate Ringer's solution and lactate Ringer's solution on the internal environment and hemodynamics of patients during laparoscopic liver resection, to observe the application prospect of sodium bicarbonate Ringer's solution in Laparoscopic hepatectomy.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
1. ≥18 years old,
2. patients who plan to undergoing laparoscopic hepatectomy ;
3. Willing to sign informed consent.
Exclusion Criteria:
1. age \<18 years
2. pregnancy
3. active cardiac conditions (unstable coronary syndromes, decompensated heart failure, significant arrhythmias, severe valvular disease, history of congestive heart failure)
4. history of significant cerebrovascular disease
5. restrictive or obstructive pulmonary disease
6. uncontrolled hypertension
7. renal dysfunction (glomerular filtration rate \<60 mL/min),
8. evidence of hepatic metabolic disorder (bilirubin \>35 mmol/L)
9. presence of active infection
Primary outcome measure(s)
lactic values — From date of randomization until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 1 month. to compare the conditions of acid-base balance and internal environment between the two groups
Trial sites (1)
Facility
City
Region
Status
Shijiang Liu
Nanjing
Jiangsu
Recruiting
More The First Affiliated Hospital with Nanjing Medical University trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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