Coronary Computed Tomography Angiography: Intervention strategies according to CCTA results
Traditional cardiovascular risk stratification: Intervention strategies according to traditional cardiovascular risk stratification based on Chinese guidelines for lipid management (2023)
Study summary
The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy improves lipid-lowering treatment and cardiovascular risk factor control compared with traditional CHD prevention strategy, guided by a cardiovascular risk score.
Eligibility
Sex
ALL
Min age
40 Years
Max age
69 Years
Healthy volunteers
No
Inclusion Criteria:
1. Nanjing residents who have no plans to leave in the next 5 years
2. Aged from 40 to 69 years
3. Free of any known clinically cardiovascular disease Able to comprehend and sign an informed consent form
Exclusion Criteria:
1. Serious liver dysfunction, defined as AST or ALT \> 3 times the normal upper limit
2. Chronic kidney disease (CKD) \> stage 4, defined as eGFR \< 30 ml/min/1.73 m2
3. Prior CCTA or invasive coronary angiography within the last 5 years
4. Any contraindications for CCTA
5. Previous use of statin or non-statin lipid-lowering medication (such as ezetimibe, PCSK9 inhibitor and XueZhiKang)
6. Life expectancy \< 3 years
7. Other reasons the researcher deems inappropriate to attend
Primary outcome measure(s)
The proportion of participants taking lipid-lowering medication regularly at both 6 and 12 months — 12 months Taking lipid-lowering medication regularly defined as taking the established lipid-lowering medication (including statin, ezetimibe, xuezhikang and PCSK9 inhibitor) at least 24 days during the past 30 days.
Trial sites (1)
Facility
City
Region
Status
Research Institute Of Medical Imaging Jinling Hospital
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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