Comparison of Two Stapled Antimesenteric Anastomosis for CD: a Randomized Control Trial Study

NCT05658081 · tracked via the Priya Life Science China tracker

Sponsor

Jinling Hospital, China

Phase

Not applicable

Started

2022-12-08

Last updated

2022-12-20

Condition(s) studied

Crohn DiseaseRecurrence

Investigational drug(s) / intervention(s)

Kono-S groupSide-to-side group

Kono-S group: patients in this arm will receive stapled Kono-S anastomosis after bowel resection

Side-to-side group: patients in this arm will receive stapled antimesenteric isoperistaltic side-to-side anastomosis after bowel resection

Study summary

The postoperative recurrence of Crohn's diseases (CD) remains high. Stapled anti-mesenteric functional end-to-end anastomosis was safe for CD patients. Its impact on the postoperative recurrence of CD was unknown. Whether it is superior than the conventional anastomosis (stapled antimesenteric isoperistaltic side-to-side anastomosis) needs explored. The trial aims to compare the different impacts of the two antimesenteric anastomosis configurations on the anastomotic recurrence following bowel resection.

Eligibility

Sex

ALL

Min age

16 Years

Max age

60 Years

Healthy volunteers

Inclusion Criteria: * patients with Crohn's disease needing bowel resection and anastomosis; * ileocolic anastomosis； * written consent acquired Exclusion Criteria: * patients underwent enterostomy; * small bowel anastomosis; * anticipating other trial.

Primary outcome measure(s)

the endoscopic recurrence rate at 1 year after surgery — at 1 year after surgery(6-18month)
the endoscopic recurrence rate at 1 year after surgery

Trial sites (1)

Facility	City	Region	Status
Department of General Surgery, Jinling hosptal,Medical School of Nanjing University	Nanjing	Jiangsu	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05658081 on ClinicalTrials.gov ↗ ← All trials in China