Observational Study About Patients Diagnosed With NAFLD

NCT05625750 · tracked via the Priya Life Science China tracker

Sponsor

Xiangya Hospital of Central South University

Phase

Observational

Started

2022-04-27

Last updated

2022-11-30

Condition(s) studied

Nonalcoholic Fatty Liver Disease

Study summary

Nonalcoholic fatty liver disease (NAFLD) is the most common condition affecting the liver, owing to its association with obesity and the metabolic syndrome. The largest study to date using magnetic resonance spectroscopy to quantify liver triglyceride (TG) content showed that approximately 33% of individuals have hepatic steatosis. NAFLD encompasses a continuum of histological findings that starts with steatosis that can progress to nonalcoholic steatohepatitis (NASH), which is characterized by inflammation and cell death, and eventually cirrhosis. Given the large number of individuals afflicted with this condition, there is a clear need to develop effective and safe therapies to treat NAFLD.

Eligibility

Sex

ALL

Min age

18 Years

Max age

75 Years

Healthy volunteers

Accepted

Inclusion Criteria: 1\. patients diagnosed with nonalcoholic fatty liver disease Exclusion Criteria: 1. patients suspected of excessive alcohol consumption 2. malignant tumors, dementia, active tuberculosis, AIDS, organ failure, pregnancy or breastfeeding, etc cannot cooperate with the investigation 3. incomplete data such as HBV serological results and abdominal ultrasound results 4. patients who refuse to sign informed consent

Primary outcome measure(s)

BMI — 3 weeks
BMI stands for body mass index. This is the ratio of a person's height to their weight.
alcohol intake — 3 years
alcohol consumption every week

Trial sites (1)

Facility	City	Region	Status
Department of Infectious Disease, Xiangya Hospital, Central South University	Changsha	Hunan	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05625750 on ClinicalTrials.gov ↗ ← All trials in China