Efficacy and Safety of Mirabegron in Intracerebral Hemorrhage

Inclusion Criteria: 1. Male or female patients aged above 18 years old. 2. The volume of the hematoma is 5-30 ml (including the cerebral cortex; Putamen, thalamus, caudate nucleus and related deep tracts; Cerebellar hemorrhage), which determined by CT scan. 3. The onset of cerebral hemorrhage symptoms or the time from last normal to detection is not more than 72 hours. 4. Patients with Glasgow Coma Scale (GCS) score ≥6 and \< 12. 5. Before the onset of the disease, function was independent and mRS score\<1. 6. Able and willing to sign written informed consent and comply with the requirements of the research protocol. Exclusion criteria: 1. Multifocal cerebral hemorrhage, brain stem hemorrhage, or ventricular hemorrhage. 2. Secondary cerebral hemorrhage caused by aneurysm, brain tumor, arteriovenous malformation, thrombocytopenia, coagulation disorder, traumatic brain injury, etc. 3. Patients who require hematoma removal surgery or other emergency surgical interventions (such as decompressive craniectomy), or who are critically ill and close to death. 4. Patients who interfere with drug use due to nausea or vomiting. 5. Combined with the following conditions that preclude participation in the study due to other systemic diseases: Severe hepatic or renal impairment, atrial fibrillation or tachycardia, pulmonary infection, severe urinary tract infection, severe urinary tract obstruction, medically uncontrolled hypertension (systolic blood pressure ≥180mmHg or diastolic blood pressure ≥110mmHg), pregnant and lactating women, and a history of malignant tumors within 5 years.