COVID-19 Immunity and Changes Over Time

NCT05271669 · tracked via the Priya Life Science China tracker

Sponsor

Chinese University of Hong Kong

Phase

Observational

Started

2022-06-06

Last updated

2026-03-18

Condition(s) studied

COVID-19

Study summary

The risk of household spread of SARS-CoV-2 hinges on both the transmission dynamics of the virus circulating in the community as well as the seroprotection pattern of constituent members, which can be attributed to vaccination and previous infections. This study is conceptualised to assess the dynamicity of SARS-CoV-2 risk at the household level, through monitoring the pattern of seroprotection, in conjunction with the vaccination coverage, history of infection and exposure risk in the setting of Hong Kong.

Eligibility

Sex

ALL

Min age

—

Max age

—

Healthy volunteers

Inclusion Criteria: * adults of age 18 or above, or children under the age of 18 with informed consent of the legal guardian * normally residing in Hong Kong * could communicate in spoken and written Chinese and/or English Exclusion Criteria: * individuals with mental illness * prisoners

Primary outcome measure(s)

Proportion of participants with COVID-19 protective immunity — 1 year
Prevalence of SARS-CoV-2 spike antibody
Proportion of participants with marker of past COVID-19 infection — 1 year
Prevalence of SARS-CoV-2 nucleocapsid antibody

Trial sites (1)

Facility	City	Region	Status
Shui Shan Lee	Hong Kong	HONG KONG	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05271669 on ClinicalTrials.gov ↗ ← All trials in China