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Clinical Trials in China / NCT05120180
Active, not recruiting Not applicable

Effect of ALND With Vein Branches Reservation on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer

NCT05120180 · tracked via the Priya Life Science China tracker
Sponsor
Xiangyun Zong
Phase
Not applicable
Started
2022-01-03
Last updated
2024-09-19

Condition(s) studied

Breast Cancer Lymphedema

Investigational drug(s) / intervention(s)

axillary lymph node dissection with vein branches reservationaxillary lymph node dissection without vein branches reservation

axillary lymph node dissection with vein branches reservation: Spare the vein branches when ALND being performed

axillary lymph node dissection without vein branches reservation: Don't spare the vein branches when ALND being performed

Study summary

The purpose of this study is to compare the effects of axillary lymph node dissection with or without axillary vein branches reservation on the affected upper limb edema and dysfunction in breast cancer patients, and to explore the solutions to prevent the affected upper limb edema and dysfunction after ALND.

Eligibility

Sex
ALL
Min age
18 Years
Max age
69 Years
Healthy volunteers
No
Inclusion Criteria: * Age 18-69 years old, * Regardless of gender, * Breast masses were diagnosed by histology and pathology, stage II -III. * Clinical palpation of axillary lymph nodes is positive, or * Axillary lymph node puncture pathology is positive, or * The multidisciplinary treatment cooperation group (MDT) recommends axillary lymph node dissection, * Good physical state score (0-2), * No severe organ complications, * No congenital or acquired diseases affecting the normal morphology and functional activities of the upper limbs, * Informed consent, understanding and compliance with research requirements. Exclusion Criteria: * Pregnancy or lactation, * Inflammatory breast cancer, * Clinical findings of metastatic lesions, * Sentinel lymph node biopsy was negative, * History of upper limb or shoulder, chest, back trauma or surgery, * Previous history of local radiotherapy, * History of other tumors, * Vascular embolic disease, * Those who are unable to comply with the clinical trial requirements for any reason.

Primary outcome measure(s)

Trial sites (3)

FacilityCityRegionStatus
Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai Shanghai Municipality
Zhejiang Cancer Hospital Hangzhou Zhejiang
Shanghai Fengxian Central Hospital Shanghai China
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05120180 on ClinicalTrials.gov ↗ ← All trials in China