axillary lymph node dissection with vein branches reservationaxillary lymph node dissection without vein branches reservation
axillary lymph node dissection with vein branches reservation: Spare the vein branches when ALND being performed
axillary lymph node dissection without vein branches reservation: Don't spare the vein branches when ALND being performed
Study summary
The purpose of this study is to compare the effects of axillary lymph node dissection with or without axillary vein branches reservation on the affected upper limb edema and dysfunction in breast cancer patients, and to explore the solutions to prevent the affected upper limb edema and dysfunction after ALND.
Eligibility
Sex
ALL
Min age
18 Years
Max age
69 Years
Healthy volunteers
No
Inclusion Criteria:
* Age 18-69 years old,
* Regardless of gender,
* Breast masses were diagnosed by histology and pathology, stage II -III.
* Clinical palpation of axillary lymph nodes is positive, or
* Axillary lymph node puncture pathology is positive, or
* The multidisciplinary treatment cooperation group (MDT) recommends axillary lymph node dissection,
* Good physical state score (0-2),
* No severe organ complications,
* No congenital or acquired diseases affecting the normal morphology and functional activities of the upper limbs,
* Informed consent, understanding and compliance with research requirements.
Exclusion Criteria:
* Pregnancy or lactation,
* Inflammatory breast cancer,
* Clinical findings of metastatic lesions,
* Sentinel lymph node biopsy was negative,
* History of upper limb or shoulder, chest, back trauma or surgery,
* Previous history of local radiotherapy,
* History of other tumors,
* Vascular embolic disease,
* Those who are unable to comply with the clinical trial requirements for any reason.
Primary outcome measure(s)
short-term Incidence of lymphedema — 1-, 6-, and 12-month short-term Incidence of upper limb lymphedema on affected side after operation
short-term Incidence of dysfunction — 1-, 6-, and 12-month short-term Incidence of upper limb dysfunction on affected side after operation
Trial sites (3)
Facility
City
Region
Status
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Shanghai
Shanghai Municipality
Zhejiang Cancer Hospital
Hangzhou
Zhejiang
Shanghai Fengxian Central Hospital
Shanghai
China
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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