This study is aimed to collect and analyze clinical data of patients with chronic viral hepatitis in the real world, to investigate the long-term outcome of these patients and to optimize treatment options based on these data.
Eligibility
Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
1. Informed consent of patients.
2. Evidence of persistent virus infection for greater than six months \[hepatitis C virus(HCV) RNA positive, hepatitis B surface antigen(HBsAg) or hepatitis B virus(HBV) DNA positive\]
Exclusion Criteria:
1. Serious psychiatric history, especially depression.
* Severe mental illness is defined as major depression or psychosis, suicide attempts, hospitalization due to mental illness or a period of disability due to mental illness.
2. Patients with serious diseases of heart, lung, kidney, brain, blood and other important organs.
3. Patients with malignant tumors (excluding those cured).
Primary outcome measure(s)
Virologic responses(for both chronic hepatitis B and C) — 24 weeks after treatment initiation Sustained virological response （Able to sustain an undetectable viral load for a period）
Serological responses(for chronic hepatitis B only) — 48 weeks after treatment initiation Hepatitis B e antigen (HBeAg) seroconversion(HBeAg loss and presence of anti-HBe) and hepatitis B surface antigen(HBsAg) seroconversion (HBsAg loss and presence of anti-HBs)
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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