Cerebral Venous Thrombosis Cohort Study in China Mainland

NCT03919305 · tracked via the Priya Life Science China tracker

Sponsor

Capital Medical University

Phase

Observational

Started

2019-01-01

Last updated

2026-06-02

Condition(s) studied

Cerebral Venous Sinus ThrombosisDeep Cerebral Vein ThrombosisCortical Vein Thrombosis

Study summary

This study was aimed to reveal the clinical features,natural history of the diseases and current therapeutic situations of cerebral venous thrombosis (CVT) in China mainland. Blood samples and cerebrospinal fluid samples will be collected after recruitment to reveal the pathological mechanisms of CVT and identify the biomarkers for CVT.

Eligibility

Sex

ALL

Min age

—

Max age

—

Healthy volunteers

Inclusion Criteria: • Cerebral venous sinus thrombosis, deep cerebral vein thrombosis and cortical vein thrombosis diagnosed by digital subtraction angiography (DSA), magnetic resonance venography (MRV), computed tomography venography (CTV) or high-resolution magnetic resonance imaging (HR-MRI). Exclusion Criteria: • None of the patient, trustee or immediate family members signed the informed consent.

Primary outcome measure(s)

Death rate — 1 year from baseline
A combination of death form of all causes
Functional independence — 1 year from baseline
Defined as modified Rankin score (0-5) equal to or lower than 2
Recurrence of cerebral venous sinus thrombosis, deep cerebral venous thrombosis and cortical vein thrombosis — 1 year from baseline
Diagnosed by DSA, MRV, CTV or HR-MRI
Incidence of hemorrhagic complication — 1 year from baseline
Extracranial hemorrhage (fall in hemoglobin of 2 gram/dl or more within 48 hours) or intracranial hemorrhage
Incidence of sinus wall rupture — 1 year from baseline
Incidence of acute ischemic stroke — 1 year from baseline
Incidence of acute myocardial infarction — 1 year from baseline
Incidence of pulmonary embolism — 1 year from baseline
Incidence of deep venous thrombosis — 1 year from baseline

Trial sites (1)

Facility	City	Region	Status
Xuanwu Hospital, Capital Medical University	Beijing	China	Recruiting

More Capital Medical University trials in China

Suraxavir Marboxil And Oseltamivir for Influenza Prophylaxis Under a Hospital-based Setting Recruiting

Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma Recruiting

Effects of Tracheostomy Decannulation on Respiratory Function Recruiting

Prognostic Biomarkers for Selective Intra-Arterial Cooling Infusion Combined with Endovascular Thrombectomy in Acute Ischemic Stroke Based on Proteomics and Metabolomics. Recruiting

Evaluating the Short-term Efficacy of Two Oscillation Techniques in Hypersecretive Mechanically Ventilated Patients Recruiting

Other trials for the same condition

Glymphatic Function and White Matter Integrity in Cerebral Venous Disorders Starting soon

Endovascular Treatment or Standard Medical Care for Cerebral Venous Sinus Thrombosis(ESCORT) Active, not recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03919305 on ClinicalTrials.gov ↗ ← All trials in China