Resection for primary lesion and cervical lymph node dissectionResection for primary lesion only
Resection for primary lesion and cervical lymph node dissection: Resection for primary lesion and cervical lymph node dissection are performed in the early-stage oral squamous cell carcinoma.
Resection for primary lesion only: Only resection for primary lesion is performed in the early-stage oral squamous cell carcinoma.
Study summary
The purpose of this study is to determine whether cervical lymph node dissection is necessarily performed in the presence of early-stage oral squamous cell carcinoma.
Eligibility
Sex
ALL
Min age
20 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria:
1. Han race;
2. Oral squamous cell carcinoma is confirmed by pathology;
3. The section of oral squamous cell carcinoma including primary two-thirds prior to the tongue, buccal mucosa， gingiva， mouth floor， hard palate mucosa;
4. The primary lesion is no more than 4cm;
5. Do not find cervical lymph node metastases and distant metastasis in the clinical examination including physical examination and MRI;
6. Patients and families agree to participate in the study;
7. Patients do not have cognitive disorders.
Exclusion Criteria:
1. Do not meet the inclusion criteria;
2. The primary lesion is more than 4cm or invade adjacent tissues;
3. Do not review on schedule;
4. Patients receive not only surgical procedures, but other antineoplastic treatment;
5. There are serious adverse events after operation;
6. Patients quit the study voluntarily;
7. Patients quit the study because of physical condition.
Primary outcome measure(s)
Five-year survival rate — After the first year, review every three months at a time；The next four years, review every six months at a time. The time from the first operation to death was recorded
Disease free survival — After the first year, review every three months at a time；The next four years, review every six months at a time. The time from the start of surgery to the discovery of the first cervical lymphatic metastases
Trial sites (1)
Facility
City
Region
Status
Guanghua School of Stomatolagy, Hospital of Stomatology Sun Yat-sen University
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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