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Trackers› Clinical trials› Locally Advanced Rectal Cancer (LARC)
Clinical trial register · China

Locally Advanced Rectal Cancer (LARC) Trials in China, 2026

Every study on the ClinicalTrials.gov registry that lists a site in China and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 19052 matching records held by the registry are in this view. Synced 22 Sep 2026, 11:10 UTC
19052
Studies in scope
all four open statuses
11786
Recruiting now
open to new participants
2009
Lead sponsors
across recruiting studies
Top sites
Beijing 4 Chengdu 2 Shanghai 2 Shenzhen 1 Tianjin 1
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Recruitment status
Phase
Site location
Beijing4 Chengdu2 Shanghai2 Shenzhen1 Tianjin1
All 8 locations
Target enrolment
to

Locally Advanced Rectal Cancer (LARC) trials in China

12 of 19052 studies
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Status
Study
Lead sponsor
Phase
Enrol
Chinese sites
Start
Not yet open
Serine/Glycine-Restricted Diet With Chemoradiotherapy for Rectal Cancer
NCT07811076Locally Advanced Rectal Cancer (LARC)
Xuelei Ma MD
Phase 1/2
140
Chengdu
2026-08-31
Not yet open
To Explore a Single-arm Phase II Study on Intestinal Microbiota Transplantation Combined With Neoadjuvant Immunotherapy and Chemoradiotherapy for Locally Advanced Rectal Cancer Under MSS/pMMR
NCT07738042Locally Advanced Rectal Cancer (LARC)
Tianjin Medical University Cancer Institute and Hospital
Not applicable
46
Tianjin
2026-07-31
Not yet open
Short-Course Online Adaptive Radiotherapy Combined With Chemotherapy, Targeted Therapy and Immunotherapy as Total Neoadjuvant Therapy (TNT) for Locally Advanced Rectal Cancer
NCT07581626Locally Advanced Rectal Cancer (LARC)
Chinese PLA General Hospital
Phase 2
60
Beijing
2026-05-01
Not yet open
SCRT Based iTNT vs. LCRT Based TNT for MSS Locally Advanced Rectal Cancer
NCT07551479Locally Advanced Rectal Cancer (LARC), MSS (Microsatellite Stable)
Fudan University
Phase 3
612
Shanghai
2026-05-01
Recruiting
Application and Exploration of Personalized ctDNA-MRD Detection Technology in Predicting the Efficacy of Neoadjuvant Therapy for Rectal Cancer
NCT07393048Locally Advanced Rectal Cancer (LARC)
Beijing Friendship Hospital
Observational
60
Beijing
2026-02-15
Recruiting
A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Cancer
NCT07347951Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Wenzhou Medical University
Phase 2
30
Wenzhou
2025-12-01
Recruiting
Optimizing Immunotherapy Combined With Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer
NCT07040098Locally Advanced Rectal Cancer (LARC)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Phase 2
228
Beijing, Shenzhen
2025-06-01
Active, closed
PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer
NCT06933251Locally Advanced Rectal Cancer (LARC)
Guangdong Provincial People's Hospital
Phase 2
30
Guangzhou
2025-04-20
Recruiting
SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer
NCT06864013Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Zhejiang University
Phase 2
116
Hangzhou
2025-01-06
Recruiting
Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study
NCT07020247Locally Advanced Rectal Cancer (LARC), Immunotherapy, Radiotherapy, Total Neoadjuvant Therapy
West China Hospital
Phase 3
184
Chengdu
2024-11-19
Active, closed
A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy in Combination With PD1 Monoclonal Antibody in MSS/pMMR Locally Advanced Rectal Cancer
NCT06688786Locally Advanced Rectal Cancer (LARC)
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Not applicable
30
Shanghai
2024-11-01
Recruiting
Application of PET/MRI in the Evaluation of the Efficacy of Neoadjuvant Therapy for Locally Advanced Rectal Cancer
NCT06653452Locally Advanced Rectal Cancer (LARC)
Peking Union Medical College Hospital
Not applicable
30
Beijing
2024-07-01
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Chinese investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 25 September 2026. https://priyalifescience.com/clinical-trials-china/condition/locally-advanced-rectal-cancer-larc

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in China and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 19,052 studies in total at the last sync on 22 Sep 2026, 11:10 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 12 of those studies listing the condition Locally Advanced Rectal Cancer (LARC).

How many Locally Advanced Rectal Cancer (LARC) trials are recruiting in China?

6 of the 12 studies on this page are recruiting new participants as of the 22 Sep 2026, 11:10 UTC sync. A further 4 have not yet opened recruitment, 2 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Locally Advanced Rectal Cancer (LARC)), 12 studies
PhaseStudiesRecruitingShare
Phase 25341.7%
Not applicable3125%
Phase 32116.7%
Observational118.3%
Phase 1/2108.3%

Most active sponsors

Lead sponsors with the most studies (Locally Advanced Rectal Cancer (LARC))
Lead sponsorStudiesRecruiting
Beijing Friendship Hospital11
Cancer Institute and Hospital, Chinese Academy of Medical Sciences11
Chinese PLA General Hospital10
First Affiliated Hospital of Wenzhou Medical University11
First Affiliated Hospital of Zhejiang University11
Fudan University10
Guangdong Provincial People's Hospital10
Peking Union Medical College Hospital11
Tianjin Medical University Cancer Institute and Hospital10
West China Hospital11
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and India registers.