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Clinical Trials in Canada / NCT06396325
Recruiting Not applicable

A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy

NCT06396325 · tracked via the Priya Life Science Canada tracker
Sponsor
Maryam Oskoui, MD, MSc, FRCPC, FAAN
Phase
Not applicable
Started
2024-11-01
Last updated
2025-07-08

Condition(s) studied

Spinal Muscular Atrophy

Investigational drug(s) / intervention(s)

Tales from the Magic Keep™Usual Care

Tales from the Magic Keep™: Exergame targeting upper limb and trunk movement designed for use on the Microsoft Azure Kinect Dose: At least 3 times a week for 20 minutes over 8 weeks (8 hours total) Continue with regularly accessed physical activities and rehabilitation services

Usual Care: Continue with regularly accessed physical activities and rehabilitation services

Study summary

This is a multisite randomized controlled registry-based trial to evaluate the efficacy of an 8-week home-based exergaming intervention as compared to usual care on occupational satisfaction of children and youth (8-18 years old age) with spinal muscular atrophy (SMA).

Eligibility

Sex
ALL
Min age
8 Years
Max age
18 Years
Healthy volunteers
No
Inclusion Criteria: * Confirmed genetic diagnosis of 5q SMA * Age at screening: Aged 8-18 years old * Participant is able to stay seated independently without support for at least 10 seconds * Participants has a score of at least 2 points in entry item A of the RULM (i.e., "Can raise 1 or 2 hands to the mouth but cannot raise a 200 g weight in it to the mouth") * Treated with disease-modifying therapy * Signed ICF Exclusion Criteria: * Inability to comply with study procedures according to the site investigator, prior to randomization * Severe scoliosis or contractures that would interfere with gameplay or with successful completion of functional assessments, as confirmed by the clinical evaluator * Planned orthopedic surgery 6 months prior to or throughout intervention and follow-up period (16 weeks post randomization) * Inability to read in English or French

Primary outcome measure(s)

Trial sites (5)

FacilityCityRegionStatus
Alberta Children's Hospital Calgary Alberta Recruiting
BC Children's Hospital Vancouver British Columbia Recruiting
IWK Health Services Halifax Nova Scotia Recruiting
Hospital for SickKids Toronto Ontario Recruiting
Centre de readaptation Marie-Enfant Montreal Quebec Recruiting

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06396325 on ClinicalTrials.gov ↗ ← All trials in Canada