Transitioning to Home or In-center Dialysis

Condition(s) studied

Investigational drug(s) / intervention(s)

Exposure: Home dialysis or facility-hemodialysis: Initiation of dialysis with home dialysis (peritoneal dialysis or home hemodialysis) or facility-hemodialysis

Study summary

For people with advanced kidney disease, deciding which type of dialysis is best can be challenging. Studies have shown that quality of life is very important to patients. It is thought that the quality of life of people receiving their dialysis at home may be better than the one of people receiving dialysis in a hospital. However, how the start of dialysis changes the quality of life of people who choose home dialysis in comparison to people choosing dialysis in a hospital is still unknown.

TRANSIT-CARE is a prospective mixed methods study following adult with advanced kidney disease who progress to dialysis and receive home or hospital-based dialysis. This study aims to examine the trajectory and change in patients' quality of life and their frailty status (health, mobility and function) before start of dialysis and up to 12-month after start. Differences between people doing home dialysis and hospital-based dialysis will be assesses taking into account people's characteristics including their gender and socio-demographics characteristics. The study will include questionnaires to measure quality of life and tools to evaluate frailty. Additionally, semi-structured interviews will be done with a diverse group of patients and caregivers before and after the initiation of dialysis to better understand their experience of transitioning to dialysis.

Eligibility

Primary outcome measure(s)

• Change in Kidney Disease Quality of Life - 36 (KDQOL-36) - Patients — From study inclusion until 12-months after dialysis start.
  Scale from 0-100 (0=poor , 100 = excellent )
• Change in 'ZARIT' burden Interview (ZBI) - Caregivers — From study inclusion until 12-months after dialysis start.
  Scale 0-88 (0=no/little burden, 88 = severe burden)

Trial sites (1)

More Ciusss de L'Est de l'Île de Montréal trials in Canada

Other trials for the same condition