PECS Study for CIED Implantation Surgery

NCT04577690 · tracked via the Priya Life Science Canada tracker

Sponsor

The Hospital for Sick Children

Phase

Phase 4

Started

2019-12-01

Last updated

2026-04-23

Condition(s) studied

Pain, PostoperativeChildAdolescent

Investigational drug(s) / intervention(s)

Bupivacaine 0.25% with epinephrine 1:200000 by PECS block and wound infiltrationBupivacaine 0.25% with epinephrine 1:200000 by wound infiltration only

Bupivacaine 0.25% with epinephrine 1:200000 by PECS block and wound infiltration: The anesthesiologist will administer bupivacaine 0.25% with epinephrine 1:200000 by PECS block after induction of anesthesia before surgical incision. The EP cardiologist will also administer bupivacaine 0.25% with epinephrine 1:200000 by infiltrating the wound after surgery is complete.

Bupivacaine 0.25% with epinephrine 1:200000 by wound infiltration only: The EP cardiologist will administer Bupivacaine 0.25% with epinephrine 1:200000 by infiltrating the wound after surgery is complete.

Study summary

We aim to determine whether pectoral nerve block (PECS) performed after induction of anesthesia but before surgical incision results less opioid use in the post operative period compared with local infiltration alone in children undergoing Cardiac Implantable Electronic Device (CIED) surgery.

Eligibility

Sex

ALL

Min age

3 Years

Max age

18 Years

Healthy volunteers

Inclusion Criteria: • All patients 3-18 years undergoing CIED surgery in the chest Exclusion Criteria: * Children \< 3 years of age at time of procedure as bupivacaine is not licensed for this age group. * No parental or patient consent * Allergy to bupivacaine * Pregnancy or lactation * Any condition or diagnosis, that could in the opinion of the Principal Investigator or delegate interfere with the participant's ability to comply with study instructions, might confound the interpretation of the study results, or put the participant at risk.

Primary outcome measure(s)

Postoperative morphine consumption — 0 hours
Amount of morphine or morphine equivalents used after surgery

Trial sites (1)

Facility	City	Region	Status
Hospital for Sick Children	Toronto	Ontario	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04577690 on ClinicalTrials.gov ↗ ← All trials in Canada