A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease

NCT04464655 · tracked via the Priya Life Science Canada tracker

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Phase

Observational

Started

2019-12-12

Last updated

2024-10-24

Condition(s) studied

Coronary Artery DiseaseMyocarditisInfiltrative CardiomyopathyDilated CardiomyopathyHypertrophic CardiomyopathyAortic Valve StenosisAortic Valve RegurgitationPericardial EffusionCongenital Heart DiseaseVascular Anomaly

Study summary

This study aims to identify and assess new CMR techniques that can improve current CMR protocols.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Accepted

Healthy Volunteers Inclusion Criteria: * Age: \> 18y, Informed consent No known current or pre-existing significant medical conditions that would affect the cardiovascular or respiratory system Exclusion Criteria: * General MRI contraindications: MR- incompatible devices such as pacemakers, defibrillators, or implanted material or foreign bodies. Consumption of caffeinated drinks or foods (including cocoa and chocolate) during the 12 hours prior to the exam.Regular nicotine consumption during the last 6 months Patients Inclusion Criteria: * Age: \>18 y, Informed consent, Clinically indicated CMR exam Exclusion Criteria: * General MRI contraindications: MR- incompatible devices such as pacemakers, defibrillators, or implanted material or foreign bodies Vasoactive medication (e.g. nitro) during the 12 hours prior to the exam. Consumption of caffeinated drinks or foods (including cocoa and chocolate) during the 12 hours prior to the exam. Regular nicotine consumption during the last 6 months

Primary outcome measure(s)

Primary diagnosis comparison between SMART CMR and standard CMR — 2019-2025
(All patients) Agreement of the suggested primary diagnosis derived from SMART CMR, compared with the diagnosis established from standard CMR protocols, using the final clinical diagnosis as established by the treating physician, as a standard of truth. If the latter is not available, the conclusions based on the results of the standard CMR protocol will be used as the standard of truth.
Main finding comparison between SMART CMR and standard CMR in patients with suspected coronary artery disease — 2019-2025
(Patients with suspected coronary artery disease:) Agreement of the main finding regarding the presence of a coronary territory at risk for inducible myocardial ischemia myocardial derived from OS-CMR, compared with standard first-pass perfusion CMR, using the coronary angiography report as a standard of truth. If the latter is not available, the conclusions based on the results of the standard CMR first pass perfusion scan will be used as the standard of truth.

Trial sites (1)

Facility	City	Region	Status
McGill University Health Center	Montreal	Quebec	Recruiting

More McGill University Health Centre/Research Institute of the McGill University Health Centre trials in Canada

This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65. Recruiting

Metabolic Risk Factors and Myocardial Oxygenation Reserve Recruiting

Exploratory Observational Prospective Study in Neonatal and Pediatric Congenital Diaphragmatic Hernia Recruiting

Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer Recruiting

Development of a Patient-Reported Outcome Measure to Assess Recovery After Abdominal Surgery Active, not recruiting

Other trials for the same condition

The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial Active, not recruiting

Valve Performance of the SAPIEN 3 Ultra RESILIA Valve: A Prospective Registry With Central Echocardiography Analysis. Recruiting

Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients Active, not recruiting

Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI Recruiting

ATrial Tachycardia PAcing Therapy in Congenital Heart Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04464655 on ClinicalTrials.gov ↗ ← All trials in Canada