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Clinical Trials in Canada / NCT03802981
Active, not recruiting Observational

A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)

NCT03802981 · tracked via the Priya Life Science Canada tracker
Phase
Observational
Started
2019-01-09
Last updated
2026-02-18

Condition(s) studied

Multiple Ground Glass Opacities (GGOs)

Study summary

The purpose of this registry study is to actively monitor people with GGOs and collect information about them, so that investigators can learn more about these lesions and about the risk of developing lung cancer in study participants whose GGOs are being monitored in the active surveillance program.

Eligibility

Sex
ALL
Min age
19 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age greater than 18 years * Have two or more GGOs on initial CT imaging * GGOs must be measure ≤3.0 cm and ≥0.6 cm in the greatest dimension * GGOs must be greater than half ground glass A biopsy is not necessary for inclusion in the trial. Biopsy of a GGO, even with a diagnosis of adenocarcinoma, does not necessarily preclude enrollment in this surveillance protocol. In other words, patients with a diagnosis of adenocarcinoma are still eligible, at the discretion of the clinician and/or investigator, if they meet the above criteria. Exclusion Criteria: * Patients who are actively undergoing lung cancer treatment or have a history of lung cancer, except for cases of completely resected pathologic stage IA nonsmall cell lung cancer (NSCLC). Patients with stage IA NSCLC and multiple GGOs can enroll in this active surveillance protocol after complete resection of the NSCLC and confirmation of stage on final pathologic assessment. * The presence of any solid lesion ≥0.6 cm suspicious for malignancy. * Patients who are actively undergoing treatment for other malignancies

Primary outcome measure(s)

Trial sites (32)

FacilityCityRegionStatus
University of California San Diego San Diego California
Stanford University Medical Center (Data collection only) Stanford California
Hartford Healthcare Hartford Connecticut
Rush University Medical Center (Data collection only) Chicago Illinois
Massachusetts General Hospital Cancer Center Boston Massachusetts
Brigham and Women's Hospital Boston Massachusetts
University of Michigan Ann Arbor Michigan
Mayo Clinic Rochester Minnesota
George Washington University School of Medicine St Louis Missouri
Washington University School of Medicine St Louis Missouri
Memorial Sloan Kettering Basking Ridge Basking Ridge New Jersey
Memorial Sloan Kettering Monmouth Middletown New Jersey
Memorial Sloan Kettering Bergen Montvale New Jersey
Roswell Park Cancer Institute (Data Collection Only) Buffalo New York
Memorial Sloan Kettering Commack Commack New York
Memorial Sloan Kettering Westchester Harrison New York
Memorial Sloan Kettering Cancer Center New York New York
New York Presbyterian Hospital New York New York
Memorial Sloan Kettering Nassau Uniondale New York
Duke University Medical Center Durham North Carolina
Lehigh Valley Health Network Allentown Pennsylvania
University of Pennsylvania (Data Collection Only) Philadelphia Pennsylvania
Thomas Jefferson University Hospital Philadelphia Pennsylvania
Fox Chase Cancer Center Philadelphia Pennsylvania
Temple University Philadelphia Pennsylvania
Allegheny Health Network Pittsburgh Pennsylvania
University of Pittsburgh Medical Center Pittsburgh Pennsylvania
MD Anderson Cancer Center Houston Texas
Baylor University Medical Center Houston Texas
McMaster University (Data Collection Only) Hamilton Ontario
University Health Network Toronto Ontario
Centre Hospitalier de l'Université de Montreal Montreal Quebec

More Memorial Sloan Kettering Cancer Center trials in Canada

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03802981 on ClinicalTrials.gov ↗ ← All trials in Canada