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Clinical Trials in Canada / NCT03449953
Active, not recruiting Observational

Critical Care Outcomes of Hematologic Oncology Patients

NCT03449953 · tracked via the Priya Life Science Canada tracker
Phase
Observational
Started
2018-02-26
Last updated
2024-11-27

Condition(s) studied

Hematologic MalignancyStem Cell Transplant

Study summary

Hematologic malignancy patients are admitted to ICU in increasing numbers. Successful ICU intervention has led to an increasing number of ICU survivors; however, there is a lack of information available about these patients' long term survival and quality of life. There is little Canadian data regarding ICU survival and regarding 1-year survival and functional outcomes in this group of patients. Over 500 patients are admitted annually to Canadian ICUs with an underlying hematologic malignancy or stem cell transplant, yet there is a paucity of up to date long-term outcome data. This information will facilitate a better understanding who would best benefit from critical care interventions and the impact of critical illness on their level of function at 1 year as well as survival.

Eligibility

Sex
ALL
Min age
16 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Subjects \>16 years with Hematologic Malignancy (HM) or post Stem Cell Transplant (HCT) who require ICU admission. * HM includes: acute myeloid leukemia, acute lymphocytic leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, myeloma, lymphoma, myelofibrosis, and other myeloproliferative disorders or myelodysplastic syndromes. * HCT is defined as the transplantation of multipotent hematopoietic stem cells from bone marrow, peripheral blood, or umbilical cord blood. Exclusion Criteria: * Subjects with significant preexisting neurological or psychiatric disease will be excluded from Phase 2 (1-year follow-up) but will be included in Phase 1.

Primary outcome measure(s)

Trial sites (13)

FacilityCityRegionStatus
Foothills Hospital Calgary Alberta
University of Alberta Edmonton Alberta
Vancouver General Hospital Vancouver British Columbia
University of Manitoba Winnipeg Manitoba
Queen Elizabeth II Health Sciences Centre Halifax Nova Scotia
Juravinski Hospital Hamilton Ontario
Kingston General Hospital Kingston Ontario
Ottawa Hospital Ottawa Ontario
Sunnybrook Health Sciences Centre Toronto Ontario
Mount Sinai Hospital Toronto Ontario
University Health Network Toronto Ontario
Maisonneuve-Rosemont Hospital Montreal Quebec
Royal Victoria Hospital Montreal Quebec

More Mount Sinai Hospital, Canada trials in Canada

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03449953 on ClinicalTrials.gov ↗ ← All trials in Canada