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Trackers› Clinical trials› Depression
Clinical trial register · Canada

Depression Trials in Canada, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Canada and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 6540 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:55 UTC
6540
Studies in scope
all four open statuses
3515
Recruiting now
open to new participants
887
Lead sponsors
across recruiting studies
Top sites
Toronto 7 Regina 7 Vancouver 5 Thunder Bay 4 Ottawa 3
Narrow the registerReset
Recruitment status
Phase
Site location
Toronto7 Regina7 Vancouver5 Thunder Bay4 Ottawa3
All 11 locations
Target enrolment
to

Depression trials in Canada

33 of 6540 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
Sites in Canada
Start
Recruiting
An Ultra-Brief ICBT Intervention: The 'Things You Do' Program
NCT07806864Depression, Anxiety
University of Regina
Not applicable
250
Regina
2026-08-11
Not yet open
Comparing Outcomes of Theta Burst Stimulation in Depression Using Advanced PET Imaging
NCT07620288Depression, Depression - Major Depressive Disorder, Depressive Episode, Major Depressive Disorder (MDD)
The Royal Ottawa Mental Health Centre
Not applicable
20
Ottawa
2026-08-01
Recruiting
The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network
NCT07066631Depression, Postpartum, Anxiety, Pregnancy
Women's College Hospital
Not applicable
570
Toronto
2025-10-29
Recruiting
Feasibility and Acceptability of an E-learning Dialectical Behavior Therapy Skills Course
NCT07088939Depression - Major Depressive Disorder, Anxiety, Depression, Stress
University of Windsor
Not applicable
40
Windsor
2025-07-20
Recruiting
Brain STimulation for ANxiety and Depression in Youth
NCT06892847Anxiety Disorders, Depression
University of Calgary
Not applicable
120
Calgary
2025-07-01
Recruiting
Enhancing Internet-Delivered Cognitive Behaviour Therapy With Additional Content
NCT07095582Loneliness, Depression, Anxiety
University of Regina
Not applicable
494
Regina
2025-06-18
Not yet open
Neurocardiac Predictors of Treatment Response to RTMS in Depression
NCT05139862Depression, Treatment Resistant Depression
University of British Columbia
Not applicable
110
Vancouver
2025-05-01
Recruiting
Internet-Delivered Cognitive Behaviour Therapy for Depression and Anxiety in Perinatal Parents
NCT06881693Anxiety, Depression
University of Regina
Not applicable
60
Regina
2025-02-24
Recruiting
Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease
NCT05568498Parkinson Disease, Depression, PARKINSON DISEASE (Disorder)
University of British Columbia
Phase 2
60
Vancouver
2025-01-20
Recruiting
Nature-based Virtual Reality Intervention for Depression in Alzheimer's Disease
NCT06732128Alzheimer Disease, Depression
Centre for Addiction and Mental Health
Not applicable
50
Toronto
2025-01-06
Recruiting
The Sleep Course: An Online Sleep Intervention for Adults With Self-reported Sleep Difficulties
NCT06745349Insomnia, Depression, Anxiety
University of Regina
Not applicable
56
Regina
2024-12-10
Active, closed
Sequential Multiple Assignment Randomized Trial for Bipolar Depression
NCT06433635Bipolar I Disorder, Depression
Massachusetts General Hospital
Phase 4
2,726
Vancouver
2024-10-01
Recruiting
Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression
NCT06152705Depression, Depressive Disorder, Major, Depressive Episode
The Royal Ottawa Mental Health Centre
Not applicable
210
Ottawa
2024-09-16
Recruiting
Comparing the Efficacy of Accelerated vs. Standard fMRI-guided iTBS in Treating Adolescents Depression
NCT06528938Depression, Depressive Disorder, Major
The Royal Ottawa Mental Health Centre
Not applicable
10
Ottawa
2024-08-01
Recruiting
Assessing Social Learning and Course Delivery Timing in Internet-delivered Cognitive Behaviour Therapy for Public Safety Personnel
NCT06298279Depression, Anxiety, Stress Disorders, Post-Traumatic
University of Regina
Not applicable
164
Regina
2024-03-12
Active, closed
Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin
NCT06341426Major Depressive Disorder, Depression, Treatment-Resistant Depression, Mood Disorders
University Health Network, Toronto
Phase 2
92
Toronto
2024-02-05
Recruiting
JoyPop Mobile Mental Health App With Transitional-Aged Youth
NCT06239545Emotion Regulation, Depression, Anxiety, Stress
Lakehead University
Not applicable
110
Thunder Bay
2024-02-01
Recruiting
JoyPop Mobile Mental Health App With Youth
NCT06239519Emotion Regulation, Depression, Anxiety, Stress
Lakehead University
Not applicable
110
Thunder Bay
2024-02-01
Recruiting
JoyPop Mobile Mental Health App With Indigenous Transitional-Aged Youth
NCT05991154Emotion Regulation, Depression, Anxiety, Stress
Lakehead University
Not applicable
110
Thunder Bay
2023-08-11
Recruiting
JoyPop Mobile Mental Health App With Indigenous Youth
NCT05898516Emotion Regulation, Depression, Anxiety, Stress
Lakehead University
Not applicable
110
Thunder Bay
2023-05-26
Recruiting
Comparing Clinical Decision-making of AI Technology to a Multi-professional Care Team in ECBT for Depression
NCT05648175Depression
Dr. Nazanin Alavi
Not applicable
186
Kingston
2022-12-01
Recruiting
Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties
NCT05603000Anxiety, Depression, Behavior Problem
University of Guelph
Not applicable
200
Guelph
2022-10-11
Recruiting
Treatment Interrupts Depression Early
NCT05002309Depression
Nova Scotia Health Authority
Phase 2
100
Halifax, Montreal
2021-12-02
Recruiting
Left vs. Right Non-Inferiority Trial
NCT04999553Depression, Major Depressive Disorder, Major Depressive Episode
University of British Columbia
Not applicable
480
Vancouver, Toronto
2021-11-08
Active, closed
MST for Parkinson's Disease
NCT04784494Parkinson Disease, Depression, Movement Disorders, Major Depressive Disorder
University of British Columbia
Not applicable
20
Vancouver
2021-09-20
Recruiting
Adaptation and Pilot Testing of Web and Mobile Interface for the ATTACHโ„ข Intervention
NCT04857775Depression, Addiction, Domestic Violence, Poverty
University of Calgary
Not applicable
100
Calgary
2021-03-15
Recruiting
Internet-delivered Cognitive Behaviour Therapy for Students: Duration Preference Trial
NCT05333627Depression, Anxiety
University of Regina
Not applicable
200
Regina
2020-11-01
Recruiting
Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)
NCT04526093Pain, Sleep, Anxiety, Depression
University Health Network, Toronto
Observational
1,000
Toronto
2020-07-15
Recruiting
Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel
NCT04335487Posttraumatic Stress, Depression, Anxiety
University of Regina
Not applicable
300
Regina
2020-07-06
Active, closed
Educational and Cultural Engagement and Incidence of Health Adverse Events
NCT03987360Older Adults, Depression, Cognitive Decline
Jewish General Hospital
Observational
30,000
Montreal
2020-03-31
Active, closed
Characterizing MyMood Patterns of Use
NCT04664374Bipolar Disorder, Mood Disorders, Depression, Dysthymia
Sunnybrook Health Sciences Centre
Observational
400
Toronto
2020-01-06
Recruiting
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
NCT02443636Depression, Post Traumatic Stress Disorder, Bipolar Disorder, Mood Disorder
Nova Scotia Health Authority
Observational
30,000
Halifax
2015-05
Active, closed
CAMH PARTNERs Integrated Care Study
NCT02345122Depression, Anxiety, Alcohol Drinking
Centre for Addiction and Mental Health
Not applicable
635
Toronto
2014-11
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Canadian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 26 September 2026. https://priyalifescience.com/clinical-trials-canada/condition/depression

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Canada and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,540 studies in total at the last sync on 26 Sep 2026, 19:55 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 33 of those studies listing the condition Depression.

How many Depression trials are recruiting in Canada?

25 of the 33 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:55 UTC sync. A further 2 have not yet opened recruitment, 6 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Depression), 33 studies
PhaseStudiesRecruitingShare
Not applicable252175.8%
Observational4212.1%
Phase 2329.1%
Phase 4103%

Most active sponsors

Lead sponsors with the most studies (Depression)
Lead sponsorStudiesRecruiting
University of Regina77
Lakehead University44
University of British Columbia42
The Royal Ottawa Mental Health Centre32
Centre for Addiction and Mental Health21
Nova Scotia Health Authority22
University Health Network, Toronto21
University of Calgary22
Dr. Nazanin Alavi11
Jewish General Hospital10
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.