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Tresiba vs NovoRapid

Insulin Degludec  ·  Insulin Aspart

Both are insulins. Here is how Tresiba and NovoRapid compare on class, mechanism, dosing, approval and supply.

At a glance

TresibaInsulin Degludec
NovoRapidInsulin Aspart
Brand names
Tresiba
NovoRapid / NovoLog
Drug class
Long-acting insulin
Rapid-acting insulin
Route
Subcutaneous
Not listed
Marketed by
Novo Nordisk
Novo Nordisk
First FDA approval
25 Sep 2015
7 Jun 2000
US shortage
Not in shortage
Not in shortage

Key differences

What each one treats

TresibaInsulin Degludec

TRESIBA is indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus. Limitations of Use • Not recommended for the treatment of diabetic ketoacidosis. TRESIBA is a long-acting human insulin analog indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus ( 1 ). Limitations of Use: • Not recommended for the treatment of diabetic ketoacidosis.

NovoRapidInsulin Aspart

An injectable fast-acting insulin analogue used to control high blood sugar in patients with diabetes.

How each one works

TresibaLong-acting insulin

12.1 Mechanism of Action The primary activity of insulin, including TRESIBA, is regulation of glucose metabolism. Insulin and its analogs lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin also inhibits lipolysis and proteolysis, and enhances protein synthesis. TRESIBA forms multi-hexamers when injected into the subcutaneous tissue resulting in a subcutaneous insulin degludec depot. The protracted time action profile of TRESIBA is predominantly due to delayed absorption of insulin degludec from the subcutaneous tissue to the systemic circulation and to a lesser extent due to binding of in…

NovoRapidRapid-acting insulin

An injectable fast-acting insulin analogue used to control high blood sugar in patients with diabetes.

Related comparisons

Lantus VS Tresiba Lantus VS NovoRapid Tresiba VS Humalog NovoRapid VS Humalog

Read more

Tresiba profile NovoRapid profile Insulins All comparisons
This is not medical advice, and not a recommendation of one drug over the other.

Which medicine is right for a given person depends on their diagnosis, other conditions, other medicines, kidney and liver function, pregnancy, and cost or reimbursement — none of which this page knows. Two drugs in the same class are not automatically interchangeable. Never start, stop or switch a prescription medicine on the basis of a web page; that decision belongs to you and your clinician or pharmacist.

Class and summary text is written by the Priya Life Science editorial team. Label, mechanism, route, manufacturer and approval data come from the U.S. FDA via the openFDA API; shortage status from the FDA Drug Shortage Database. Approvals, indications and brand names differ between the US, EU/Ireland (EMA/HPRA) and other regions — a drug approved in one may not be approved, or may carry a different name, in another.