CX11: CX11 tablets administered orally once daily (QD)
Placebo: Matching placebo tablets administered orally once daily (QD)
This study is testing whether a new medication called CX11 works and is safe for participants with type 2 diabetes who have not reached good blood sugar control while taking a steady dose of metformin, with or without a steady dose of an SGLT2 inhibitor, for at least 90 days.
The study is being done at multiple medical centers. Participants are assigned by chance (randomized) to different groups, and neither the participants nor the study staff know which group they're in (double-blind). The groups are compared side by side (parallel), and some participants will receive inactive pills (placebo) to help measure the true effect of the study drug.
After screening, participants will be randomly placed into one of six groups, with equal chances of being in any group. Each group will receive a different dose of CX11 or a placebo. Treatment will last 24 weeks. After that, all participants will have a 2-week follow-up period to check on safety.
| Facility | City | Region | Status |
|---|---|---|---|
| Central Research Associates - Flourish - PPDS | Birmingham | Alabama | Recruiting |
| AES - DRS - Synexus Clinical Research US, Inc. - Birmingham | Birmingham | Alabama | Recruiting |
| AES - DRS - Optimal Research Alabama - Huntsville | Huntsville | Alabama | Recruiting |
| Core Healthcare Group | Cerritos | California | Recruiting |
| Ark Clinical Research - Long Beach | Long Beach | California | Recruiting |
| Flourish Research - Walnut Creek - PPDS | Walnut Creek | California | Recruiting |
| AES - DRS - Optimal Research Florida - Melbourne | Melbourne | Florida | Recruiting |
| Tampa General Hospital | Tampa | Florida | Recruiting |
| Conquest Research LLC - Winter Park | Winter Park | Florida | Recruiting |
| Privia Medical Group Georgia, LLC - Albany - Javara - PPDS | Albany | Georgia | Recruiting |
| Javara Inc. - Fayetteville | Fayetteville | Georgia | Recruiting |
| Privia Medical Group Georgia, LLC - Savannah - Javara - PPDS | Savannah | Georgia | Recruiting |
| Privia Medical Group Georgia, LLC - Thomasville - Javara - PPDS | Thomasville | Georgia | Recruiting |
| AES - DRS - Synexus Clinical Research US, Inc. - Chicago | Chicago | Illinois | Recruiting |
| AES - DRS - Synexus Clinical Research US, Inc. - Evansville | Evansville | Indiana | Recruiting |
| Privia Medical Group, LLC - Kelly's Collaborative Care - Javara - PPDS | Silver Spring | Maryland | Recruiting |
| Elixia Health - Springfield - Elixia - PPDS | Springfield | Massachusetts | Recruiting |
| Elixia Health - Michigan Kidney Consultants, LLC - Elixia - PPDS | Pontiac | Michigan | Recruiting |
| AES - DRS - Synexus Clinical Research US, Inc. - Edina - Minneapolis | Edina | Minnesota | Recruiting |
| Mankato Clinic - East Main Street - Javara - PPDS | Mankato | Minnesota | Recruiting |
| Sky Integrative Medical Center | Ridgeland | Mississippi | Recruiting |
| Hassman Research Institute - Berlin - CenExel - PPDS | Berlin | New Jersey | Recruiting |
| Albuquerque Clinical Trials Inc | Albuquerque | New Mexico | Recruiting |
| Brooklyn Clinical Research | Brooklyn | New York | Recruiting |
| M3 Wake Research, Inc - M3 WR | Raleigh | North Carolina | Recruiting |
| Unity Clinical Research | Oklahoma City | Oklahoma | Recruiting |
| Monroe Biomedical Research Charleston | North Charleston | South Carolina | Recruiting |
| M3 Wake Research - Dallas | Dallas | Texas | Recruiting |
| University of Texas Southwestern Medical Center | Dallas | Texas | Not Yet Recruiting |
| SMS Clinical Research, LLC - 400 W. Kearney St | Mesquite | Texas | Recruiting |
| AES - DRS - Synexus Clinical Research US, Inc. - San Antonio | San Antonio | Texas | Recruiting |
| Flourish Research - San Antonio - PPDS | San Antonio | Texas | Recruiting |
| Privia Medical Group- North Texas - Stephenville - Javara - PPDS | Stephenville | Texas | Recruiting |
| Conquest Research - Arlington | Vienna | Virginia | Recruiting |
| AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Poznaniu | Poznan | Greater Poland Voivodeship | Recruiting |
| Centrum Medyczne Pratia Bydgoszcz - PPDS | Bydgoszcz | Kuyavian-Pomeranian Voivodeship | Recruiting |
| Medyczne Centrum Diabetologiczno-Endokrynologiczno-Metaboliczne | Krakow | Lesser Poland Voivodeship | Recruiting |
| FutureMeds - Krakow - PPDS | Krakow | Lesser Poland Voivodeship | Recruiting |
| METABOLICA Sp. z o.o | Tarnów | Lesser Poland Voivodeship | Recruiting |
| AES - DRS - Synexus Polska Sp. z o.o. Oddzial we Wroclawiu | Wroclaw | Lower Silesian Voivodeship | Recruiting |
+ 8 more sites — see the full list on the official registry below.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07340320 on ClinicalTrials.gov ↗ ← All trials in the USA