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Updated 27 Aug 2026 · ClinicalTrials.gov

Clinical Trials in Ireland

Every active and recruiting clinical study with an Irish site — searchable by condition, sponsor, phase and location. Refreshed daily from the ClinicalTrials.gov registry.

52
Recruiting now
89
Active studies
Recruiting Phase 3
A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib
Myelofibrosis, Anemia
Takeda · started 2026-09-02
📍 Cork · Dublin · Galway
NCT07623161 on ClinicalTrials.gov ↗
Recruiting Phase 3
Optimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent Breast Cancer Using Genomic Tests
Early Breast Cancer, Premenopausal Breast Cancer, HR+/HER2- Breast Cancer
UNICANCER · started 2026-06-26
📍 Cork · Dublin · Limerick · Tullamore · Waterford
NCT07106632 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression
Ovarian Cancer
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc · started 2026-04-17
📍 Cork · Dublin
NCT07546500 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)
Advanced Renal Cell Carcinoma (RCC)
Bristol-Myers Squibb · started 2026-03-26
📍 Dublin
NCT07293351 on ClinicalTrials.gov ↗
Recruiting
Profiling Patients With Rotator Cuff Related Shoulder Pain: What Factors Influence Outcomes With Non-operative Care in a Secondary Care Specialist Shoulder Clinic?
Rotator Cuff Related Shoulder Pain, RCRSP
University of Limerick · started 2026-01-05
📍 Limerick
NCT07360847 on ClinicalTrials.gov ↗
Recruiting
Evaluating the De-Escalation of Surveillance for Patients Who Have Undergone Curative Treatment for Breast Cancer
Breast Cancer
Royal College of Surgeons, Ireland · started 2025-12-11
📍 Dublin
NCT07572370 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
Ovarian Cancer
Incyte Corporation · started 2025-12-09
📍 Dublin · Galway · Waterford
NCT07214779 on ClinicalTrials.gov ↗
By invitation
Impact of Cooling Mats on Vasomotor Symptoms in Patients Receiving Endocrine Therapy
Hot Flashes, Sleep, Hormonal, Cancer
Sligo General Hospital · started 2025-11-10
📍 Sligo
NCT07422727 on ClinicalTrials.gov ↗
Recruiting
Remote Vital Sign Monitoring in Palliative Care Patients Using a Wearable ECG Monitor
Cancer, Malignancies Multiple, Terminal Care, Hospice
Our Lady's Hospice and Care Services · started 2025-11-06
📍 Dublin
NCT07512505 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms, Neoplasm Metastasis
Eli Lilly and Company · started 2025-10-22
📍 Cork · Dublin
NCT07213804 on ClinicalTrials.gov ↗
Recruiting
The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Luminate Medical, Inc. · started 2025-10-03
📍 Dublin
NCT07142304 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Ulcerative Colitis
Alfasigma S.p.A. · started 2025-09-29
📍 Dublin
NCT06865417 on ClinicalTrials.gov ↗
Recruiting
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
St. James's Hospital, Ireland · started 2025-09-01
📍 Dublin
NCT07160868 on ClinicalTrials.gov ↗
Recruiting Phase 3
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
Acute Myeloid Leukemia, Adult
Stichting Hemato-Oncologie voor Volwassenen Nederland · started 2025-05-05
📍 Cork · Dublin · Galway · Waterford
NCT06652438 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
Lymphoma, Large B-Cell, Diffuse
Merck Sharp & Dohme LLC · started 2025-04-11
📍 Dublin · Limerick
NCT06890884 on ClinicalTrials.gov ↗
Active Phase 3
Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)
Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Immutep S.A.S. · started 2025-03-21
📍 Cork · Dublin
NCT06726265 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
Metastatic Castration-resistant Prostate Cancer
Celgene · started 2025-03-13
📍 Cork · Dublin
NCT06764485 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Ulcerative Colitis, Crohn's Disease
Takeda · started 2025-01-22
📍 Dublin
NCT06100289 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Clinical Trial to Evaluate Efficacy and Safety of Navepegritide in Adolescents (12 - 18 Years of Age) With Achondroplasia.
Achondroplasia
Ascendis Pharma A/S · started 2024-12-10
📍 Dublin
NCT06732895 on ClinicalTrials.gov ↗
Recruiting
Heart Failure Virtual Ward Research Study
Heart Failure
National University of Ireland, Galway, Ireland · started 2024-10-18
📍 Ballinasloe
NCT06620653 on ClinicalTrials.gov ↗
Recruiting
Microbiome Immunotherapy Neoadjuvant Assessment
Triple Negative Breast Cancer
University College Cork · started 2024-10-02
📍 Cork
NCT06709651 on ClinicalTrials.gov ↗
Recruiting
ENVELOP: Wound Care Following Pilonidal Sinus Surgery
Pilonidal Sinus, Wound Healing
Royal College of Surgeons, Ireland · started 2024-10-01
📍 Dublin · Castlebar · Kilkenny · Limerick · Tullamore · Waterford
NCT06647290 on ClinicalTrials.gov ↗
Active
Safety and Tolerance of a Novel Three-Strain Probiotic in Healthy Adults
Healthy Adults
Pendulum Therapeutics · started 2024-09-23
📍 Cork
NCT07566884 on ClinicalTrials.gov ↗
Recruiting
The Effect of a Post-operative Exercise Programme Versus Standard Care on Physical Fitness of Patients With Breast Cancer Undergoing Deep Inferior Epigastric Perforator (DIEP) Flap Reconstruction Surgery
Breast Cancer, Exercise
Royal College of Surgeons, Ireland · started 2024-08-01
📍 Beaumont
NCT07672392 on ClinicalTrials.gov ↗
Active Phase 2
SalT Supplementation in Older Adults With Orthostatic Intolerance Disorders
Orthostatic Hypotension
University of Galway · started 2024-07-09
📍 Galway
NCT06188663 on ClinicalTrials.gov ↗
Recruiting
The Effect of an Adhesive System on the Retention and Caries Prevention for Fissure Sealants in Permanent Molars
Dental Caries, Fissure Sealant
University of Dublin, Trinity College · started 2024-06-05
📍 Dublin
NCT06608563 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer
Non-Muscle Invasive Bladder Neoplasms
Janssen Research & Development, LLC · started 2024-04-18
📍 Cork · Dublin
NCT06319820 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Breast Neoplasms
Merck Sharp & Dohme LLC · started 2024-04-14
📍 Cork · Dublin
NCT06312176 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Recurrent or Metastatic Solid Tumors
Daiichi Sankyo · started 2024-04-10
📍 Dublin · Cork · Galway
NCT06330064 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Phase 1/1b Study of IAM1363 in HER2 Cancers
HER2 Mutation-Related Tumors, HER2, HER2-positive Breast Cancer, HER2 + Breast Cancer
Iambic Therapeutics, Inc · started 2024-03-25
📍 Dublin · Cork
NCT06253871 on ClinicalTrials.gov ↗
Recruiting
The NEU-STIM Trial
Infant, Premature, Diseases, Birth, Preterm
Leiden University Medical Center · started 2024-03-11
📍 Dublin · Galway
NCT05942924 on ClinicalTrials.gov ↗
Recruiting
PINTA - Prophylactic Incisional Negative Pressure Therapy for Major Amputations
Wound Surgical, Wound Infection, Cosmesis
Royal College of Surgeons, Ireland · started 2024-03-01
📍 Dublin · Galway · Limerick · Waterford
NCT06025253 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Dose-Painted Intensity Modulated Radiotherapy Pancreas (DP-IMRT Pancreas)
Pancreatic Adenocarcinoma
Cancer Trials Ireland · started 2024-01-30
📍 Dublin
NCT06024824 on ClinicalTrials.gov ↗
Recruiting
International obServational sTudy on AiRway manaGement in operAting Room and Non-operaTing Room anaEsthesia
Airway Complication of Anesthesia
University of Turin, Italy · started 2024-01-15
📍 Galway
NCT05759299 on ClinicalTrials.gov ↗
Recruiting
A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials
Relapsed/Refractory Multiple Myeloma (RRMM)
Janssen-Cilag Ltd. · started 2023-12-18
📍 Cork · Dublin · Galway
NCT06285318 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma
Diffuse Large B-cell Lymphoma (DLBCL)
Regeneron Pharmaceuticals · started 2023-12-13
📍 Dublin
NCT06091865 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
Bristol-Myers Squibb · started 2023-09-14
📍 Drogheda · Dublin
NCT06003426 on ClinicalTrials.gov ↗
Active
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation
Cardiac Arrest With Successful Resuscitation, Hypoxia, Brain
Region Skane · started 2023-08-17
📍 Dublin
NCT05564754 on ClinicalTrials.gov ↗
Active
Satisfaction, QoL,Health Status & Clinic Outcomes for Patients Attending MSK Triage Clinics in Rheumatology
Musculoskeletal Pain, Rheumatologic Disorder
Health Service Executive, Ireland · started 2023-06-22
📍 Sligo
NCT04244968 on ClinicalTrials.gov ↗
Active Phase 3
Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
AbbVie · started 2023-03-15
📍 Dublin · Cork · Galway · Sligo · Waterford
NCT05445778 on ClinicalTrials.gov ↗
Recruiting
Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis
Late-Onset Neonatal Sepsis, Extreme Prematurity, Neonatal Hypotension
Mount Sinai Hospital, Canada · started 2023-02-06
📍 Cork · Dublin
NCT05347238 on ClinicalTrials.gov ↗
Recruiting Phase 2
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Unresectable Renal Cell Carcinoma
NRG Oncology · started 2023-02-01
📍 Dublin
NCT05327686 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus
Bristol-Myers Squibb · started 2023-01-12
📍 Manorhamilton · Cork · Dublin
NCT05617677 on ClinicalTrials.gov ↗
Recruiting
European Myeloma Network (EMN) Sample Project
Multiple Myeloma, Smoldering Multiple Myeloma, Plasma Cell Leukemia, Extramedullary Myeloma
European Myeloma Network B.V. · started 2022-12-21
📍 Galway
NCT06237803 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Trial of Lu AG13909 in Participants With Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia
H. Lundbeck A/S · started 2022-12-19
📍 Dublin
NCT05669950 on ClinicalTrials.gov ↗
Recruiting Phase 2
Dazucorilant in Patients With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Corcept Therapeutics · started 2022-11-15
📍 Dublin
NCT05407324 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer · started 2022-10-24
📍 Cork · Dublin · Waterford
NCT05253651 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT
Prostate Cancer
Institute of Cancer Research, United Kingdom · started 2022-09-09
📍 Cork · Dublin · Limerick
NCT05613023 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation
Multiple Myeloma
European Myeloma Network B.V. · started 2022-09-08
📍 Cork · Dublin · Galway · Limerick
NCT05243797 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping
Duchenne Muscular Dystrophy (DMD)
Dyne Therapeutics · started 2022-08-12
📍 Dublin
NCT05524883 on ClinicalTrials.gov ↗
Active Phase 3
Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
Coronary Artery Disease
Novartis Pharmaceuticals · started 2022-07-08
📍 Dublin · Galway
NCT05360446 on ClinicalTrials.gov ↗
Active Phase 3
Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Multiple Myeloma
Celgene · started 2022-06-23
📍 Cork · Dublin · Galway
NCT04975997 on ClinicalTrials.gov ↗
Active
ProVee Urethral Expander System IDE Study (ProVIDE)
BPH With Symptomatic Lower Urinary Tract Symptoms
ProVerum Medical · started 2022-06-09
📍 Dublin
NCT05186740 on ClinicalTrials.gov ↗
Active
Evolut™ EXPAND TAVR II Pivotal Trial
Moderate Aortic Valve Stenosis
Medtronic Cardiovascular · started 2022-04-27
📍 Galway
NCT05149755 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated · started 2022-03-30
NCT05312879 on ClinicalTrials.gov ↗
Active Phase 3
Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15)
Endometrial Neoplasms
Merck Sharp & Dohme LLC · started 2022-02-03
📍 Cork · Dublin
NCT05173987 on ClinicalTrials.gov ↗
Active Phase 2
Study Assessing Long-term Safety and Efficacy of Alpelisib in Patients With PIK3CA-Related Overgrowth Spectrum (PROS) Who Previously Participated in Study CBYL719F12002 (EPIK-P1)
PIK3CA-related Overgrowth Spectrum (PROS)
Novartis Pharmaceuticals · started 2022-01-27
📍 Dublin
NCT04980833 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
Advanced Solid Tumor, Non Small Cell Lung Cancer, Untreated Advanced NSCLC, 1st Line NSCLC
Synthekine · started 2022-01-25
📍 Dublin · Galway
NCT05098132 on ClinicalTrials.gov ↗
Active
Post Marketing Clinical Follow Up of the BioProtect Balloon Implant System
Prostate Cancer
BioProtect · started 2022-01-01
📍 Dublin
NCT05354440 on ClinicalTrials.gov ↗
Active
Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer
Prostate Cancer
Boston Scientific Corporation · started 2021-12-21
📍 Cork
NCT04905069 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
Indolent Systemic Mastocytosis, Smoldering Systemic Mastocytosis
Blueprint Medicines Corporation · started 2021-11-30
📍 Cork
NCT04910685 on ClinicalTrials.gov ↗
Active Phase 3
Australasian Resuscitation In Sepsis Evaluation: FLUid or Vasopressors In Emergency Department Sepsis
Shock, Septic
Australian and New Zealand Intensive Care Research Centre · started 2021-10-26
📍 Elm Park
NCT04569942 on ClinicalTrials.gov ↗
Active Phase 2
A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus
Beeline Medicines Corporation · started 2021-10-11
📍 Dublin · Galway · Manorhamilton
NCT04895696 on ClinicalTrials.gov ↗
Active Phase 3
A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.
Follicular Lymphoma, Marginal Zone Lymphoma
Incyte Corporation · started 2021-04-15
📍 Dublin · Galway
NCT04680052 on ClinicalTrials.gov ↗
Active Phase 3
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
Myeloproliferative Disorders, Myelofibrosis, Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis
Celgene · started 2021-02-25
📍 Cork · Dublin
NCT04717414 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease
IgG4 Related Disease
Amgen · started 2020-12-04
📍 Cork
NCT04540497 on ClinicalTrials.gov ↗
Recruiting Phase 3
Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer
Esophageal Squamous Cell Carcinoma
Karolinska University Hospital · started 2020-11-27
📍 Dublin
NCT04460352 on ClinicalTrials.gov ↗
Active
First in Human Clinical Investigation of the FIRE1 System in Heart Failure Patients (FUTURE-HF)
Heart Failure
Foundry Innovation & Research 1, Limited (FIRE1) · started 2019-11-22
📍 Galway
NCT04203576 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation
Mantle Cell Lymphoma; Non-Hodgkin Lymphoma
BeOne Medicines · started 2019-08-20
📍 Cork · Dublin · Galway · Limerick · Waterford
NCT04002297 on ClinicalTrials.gov ↗
Recruiting Phase 2
Pan Tumor Rollover Study
Cancer
Bristol-Myers Squibb · started 2019-08-09
📍 Dublin · Limerick
NCT03899155 on ClinicalTrials.gov ↗
Active Phase 3
Phase III Study in First-line Treatment of Patients With Metastatic Colorectal Cancer Who Are Not Candidate for Intensive Therapy.
Metastatic Colorectal Cancer
Institut de Recherches Internationales Servier · started 2019-03-21
📍 Cork · Dublin
NCT03869892 on ClinicalTrials.gov ↗
Recruiting
The Mechanical Characterisation of Human Saphenous and Popliteal Vein
Peripheral Vascular Diseases
University Hospital of Limerick · started 2019-01-21
📍 Limerick
NCT04016649 on ClinicalTrials.gov ↗
Active Phase 3
Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)
Breast Cancer
Merck Sharp & Dohme LLC · started 2018-12-27
📍 Cork · Dublin
NCT03725059 on ClinicalTrials.gov ↗
Active Phase 2
Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)
Advanced Solid Neoplasms
Merck Sharp & Dohme LLC · started 2018-12-12
📍 Dublin · Cork
NCT03742895 on ClinicalTrials.gov ↗
Active Phase 2
To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.
Metastatic Triple Negative Breast Cancer
AstraZeneca · started 2018-03-07
📍 Cork · Dublin
NCT03330847 on ClinicalTrials.gov ↗
Active
ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population
Primary Knee Arthroplasty
DePuy Orthopaedics · started 2017-09-19
📍 Cork
NCT03153449 on ClinicalTrials.gov ↗
Active Phase 3
International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia
Acute Myeloid Leukaemia
University of Birmingham · started 2016-04
📍 Dublin
NCT02724163 on ClinicalTrials.gov ↗
Recruiting
The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue
Vascular Diseases
University Hospital of Limerick · started 2016-01-01
📍 Limerick
NCT05802706 on ClinicalTrials.gov ↗
Active Phase 3
Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery
Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Cutaneous Melanoma, Metastatic Mucosal Melanoma
National Cancer Institute (NCI) · started 2015-11-10
📍 Dublin · Galway · Waterford
NCT02506153 on ClinicalTrials.gov ↗
Recruiting
Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis
ALS (Amyotrophic Lateral Sclerosis), Postpoliomyelitis Syndrome, Spinal Muscular Atrophy
University of Dublin, Trinity College · started 2015-10-01
📍 Dublin
NCT05663008 on ClinicalTrials.gov ↗
Active Phase 3
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors
Germ Cell Tumor, Teratoma, Choriocarcinoma, Germinoma
Alliance for Clinical Trials in Oncology · started 2015-08-06
📍 Dublin
NCT02375204 on ClinicalTrials.gov ↗
Active Phase 3
PALbociclib CoLlaborative Adjuvant Study
Breast Cancer
Alliance Foundation Trials, LLC. · started 2015-08
📍 Cork · Dublin · Limerick · Sligo · Waterford
NCT02513394 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Long-term Extension Study of PCI-32765 (Ibrutinib)
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, Follicular Lymphoma
Janssen Research & Development, LLC · started 2013-09-09
📍 Dublin
NCT01804686 on ClinicalTrials.gov ↗
Recruiting
European Registry on the Management of Helicobacter Pylori Infection
H. Pylori Infection
Javier P. Gisbert · started 2013-06
📍 Dublin
NCT02328131 on ClinicalTrials.gov ↗
Recruiting
Product Surveillance Registry
Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders
Medtronic · started 2012-01
📍 Galway
NCT01524276 on ClinicalTrials.gov ↗
Active Phase 3
Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
Light Chain Deposition Disease, Smoldering Multiple Myeloma
National Cancer Institute (NCI) · started 2011-01-24
📍 Dublin · Galway
NCT01169337 on ClinicalTrials.gov ↗
Active
Male Breast Cancer: Understanding the Biology for Improved Patient Care
Breast Cancer
European Organisation for Research and Treatment of Cancer - EORTC · started 2010-12
📍 Cork · Dublin · Waterford
NCT01101425 on ClinicalTrials.gov ↗
Recruiting
Pharmacokinetics of Antiretroviral Agents in HIV-infected Pregnant Women.
HIV Infections
Radboud University Medical Center · started 2009-02
📍 Dublin
NCT00825929 on ClinicalTrials.gov ↗
Active Phase 3
Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
Breast Adenocarcinoma, Hormone Receptor Positive, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7
National Cancer Institute (NCI) · started 2006-04-07
📍 Cork · Dublin · Mount Merrion · Galway · Limerick · Sligo
NCT00310180 on ClinicalTrials.gov ↗
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Priya Life Science (2026). Clinical Trials in Ireland Tracker. Available at: https://priyalifescience.com/clinical-trials-ireland (Accessed: 27 August 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — studies listing at least one Irish site, refreshed daily. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. For trials across the wider EU, see our EU Clinical Trials Tracker.