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Clinical Trials in the EU / 2026-525318-75-00
Authorised Phase III

C6491013 - A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Once-Monthly PF-08653944 in Adults with Overweight or Obesity (VESPER 6)

2026-525318-75-00 · tracked via the Priya Life Science EU tracker
Sponsor
Pfizer Inc.
Sponsor type
Pharmaceutical company
Therapeutic area
Nutritional and Metabolic Diseases
Decision date
09/09/2026
Enrollment target
120
Sites
Spain, Germany, Italy

Condition studied

Overweight or Obesity

Investigational medicinal product(s)

PF-08653944PF-08653944PF-08653944PF-08653944Placebo to match PF-08653944

Eligibility

Age group
18-64 years, 65+ years
Sex
Female, Male

Primary endpoint

Body weight percent change from baseline (CFB) at Week 72.

Endpoint detail

Body weight (kg) CFB at Week 72., Waist circumference (cm) CFB at Week 72., SBP (mmHg) CFB at Week 72., IWQoL-Lite-CT Physical Function composite score CFB at Week 72.

Official registry record

This page summarises publicly available CTIS data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View 2026-525318-75-00 on CTIS ↗ ← All trials in the EU