No Intervention: Observational Cohort: No Intervention
Study summary
Based on the analysis of dietary characteristics, gut microbiota diversity, and composition, this study investigates the relationships between the dietary inflammatory potential, gut microbiota, and sarcopenia. Furthermore, it explores the mediating role of gut microbiota in the association between the dietary inflammatory index and the risk of sarcopenia. The findings are expected to provide insights into the mechanisms through which dietary inflammation influences the development and progression of sarcopenia, and to offer a basis for dietary and nutritional interventions aimed at preventing or managing this condition.
Eligibility
Sex
ALL
Min age
60 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Permanent residents of the community aged 60 years or older.
* Continuous residence duration in the community for more than 5 years.
Exclusion Criteria:
* Taking medications known to affect muscle function (e.g., corticosteroids, protein supplements, muscle enhancers).
* Requiring walking assistance or having severe cognitive impairment that would preclude successful completion of assessments including bioelectrical impedance analysis (BIA), gait speed measurement, and handgrip strength testing.
* Presence of a cardiac pacemaker, which contraindicates BIA measurement.
* Diagnosis of one or more chronic diseases that significantly limit dietary intake.
Primary outcome measure(s)
The prevalence of sarcopenia — Through study completion, an average of 1 year The diagnosis of sarcopenia is confirmed according to the AWGS 2019 criteria, which requires the assessment of muscle strength, physical performance, and muscle mass.
Change in absolute abundance of Faecalibacterium prausnitzii — Through study completion, an average of 1 year 16S rRNA absolute quantification was used to detect the microbial composition of the fecal samples.
Dietary Characteristics — Through study completion, an average of 1 year Dietary data were collected using a food frequency questionnaire (FFQ) to analyze dietary patterns and nutrient intake.
Trial sites (1)
Facility
City
Region
Status
Lanzhou university
Lanzhou
Gansu
Recruiting
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time on our Cookie Policy page. See also our Privacy Policy.